Previous research has shown that anxiety and depression are associated with many chronic skin diseases, including spontaneous urticaria (CSU) atopic dermatitis (AD). A causal relationship between these phenomena not yet been established. Most authors believe itchy conditions cause anxiety, depression, insomnia rather than the other way around. In our work, we attempted to assess pr...

Knowledge of the clinical course of chronic spontaneous urticaria (CSU) remains unclear. The purpose of our study was to investigate the clinical course of CSU in the Korean adult population. Each patient in the CSU group who was defined by disease codes between 2003 and 2007 was tracked whether he or she went into remission or not until 2013. Kaplan-Meier survival analysis was carried out to a...

The pathogenesis of chronic spontaneous urticaria (CSU) has not been fully understood; nevertheless, significant progress has been achieved in recent years. The aim of this study was to investigate the possible role of reactive oxygen species (ROS) in the pathogenesis of CSU. Sixty-two children with CSU and 41 healthy control subjects were enrolled in the study. An extensive evaluation of demog...

Background Atopic dermatitis (AD) and chronic spontaneous urticaria (CSU) are two prevalent, visible itching skin diseases associated with decreased quality of life (QoL), sleep disturbance, depression anxiety. However, little is known about stigmatisation among patients suffering from these diseases. Objectives To examine whether AD or CSU experience if disease severity psychosocial variables ...

Background An autoimmune basis is believed to be responsible for about half of all cases of chronic spontaneous urticaria (CSU) with specific IgG antibodies directed at the high affinity receptor sites for IgE on the mast cell. The autologous serum skin test (ASST) is used to identify this autoimmune form of CSU. Currently, basophil histamine release assay and basophil activation test (BAT) hav...

In chronic spontaneous urticaria (CSU), a decrease in the number of basophils peripheral blood (PB), or basopenia, is observed. However, its mechanism has not been clarified. Therefore, we examined whether basopenia CSU reflects infiltration inflamed skin. First, compared basophil counts PB before and after treatment. The increased following improvement symptom 15 out 17 patients treated with o...

Chronic spontaneous urticaria (CSU) is a disease with significant morbidity and relative prevalence that has important effects on the quality of life (QoL) of those who suffer from it. Omalizumab is a recombinant humanized anti-immunoglobulin E (IgE) antibody that binds to the Cε3 domain of the IgE heavy chain and prevents it from binding to its high-affinity receptor FcεRI. It has been largely...

Chronic spontaneous urticaria (CSU) is a skin disease characterised by wheal appearance, swelling, itching, and painful skin. Omalizumab has been used for CSU treatment demonstrating good efficacy. To investigate the efficacy and safety of omalizumab treatment in CSU patients in real-life practice. A retrospective analysis was performed on 38 patients suffering from CSU who received 300 mg of o...

Background and purpose: Urticaria is a pruritic cutaneous disease characterized by weal and flare.  Acute and chronic urticaria affects the quality of life. Some abnormalities are associate or comorbid with urticaria. The purpose of this study was to examine comorbid conditions in patients with urticaria.  Materials and Methods: We searched in many databases including Google Scholar, PubMed, S...