conclusions we conclude that volume of residual pneumoperitoneum is a contributing factor in the etiology of postoperative pain after laparoscopic cholecystectomy. results at the end of the study, 17 patients (30.9%) had no residual pneumoperitoneum after 24 hours; which 23 (41.81%) had mild residual pneumoperitoneum, eight (14.54%) had moderate pneumoperitoneum and seven (12.72%) had severe pn...

objectives this study aimed to assess the efficacy and safety of intramuscular pethidine as an analgesic during labor by comparing it to inhaled 50% nitrous oxide (entonox). conclusions inhaled nitrous oxide seems to give better pain relief in the short term compared to a single dose of pethidine. entonox, which is more convenient to administer than an intramuscular injection of pethidine, is a...

context lumbar central spinal stenosis is common and often results in chronic persistent pain and disability, which can lead to multiple interventions. after the failure of conservative treatment, either surgical or nonsurgical modalities such as epidural injections are contemplated in the management of lumbar spinal stenosis. evidence acquisition recent randomized trials, systematic reviews an...

conclusions nitroglycerine may be a safe and effective adjuvant therapeutic for pain reduction in patients under propofol injection. hence, its use for reduction of propofol injection-induced pain is recommended. results the pain severity in nitroglycerine group was significantly lower compared with the placebo group (p < 0.0001). moreover, the local adverse reactions were observed only in thre...

background : pain is one of the main protests of inflammatory diseases, hence, understanding the mechanisms which involved in the induction and persistence of pain is essential. microglia is a contributing factor in the onset and maintenance of inflammation. increased microglial   activation increases the level of central pro-inflammatory cytokines and the development of central sensitization f...

background : children suffering from cancer always require pain relief and reduce anxiety when undergoing painful procedures. the aim of this study is to compare the effect of pethedine and ketamine administration in cancer-diagnosed children undergoing bone marrow aspiration and biopsy procedures. subjects and methods : a randomized, double-blinded, crossover trial was carried out on 57 childr...