Background: Contrast-induced nephropathy (CIN) is defined as the absolute ≥ 0.5 mg/dL or relative > 25% increase in serum creatinine from baseline on admission to 48–72 h following exposure intravascular iodinated contrast media. The objective of this research was assess predictive value PRECISE DAPT score for development CIN acute coronary syndrome cases undergoing PCI and compare its power...

Colon cancer cells frequently display minisatellite instability (MIN) or chromosome instability (CIN). While MIN is caused by mismatch repair defects, the lesions responsible for CIN are unknown. The observation that CIN cells fail to undergo mitotic arrest following spindle damage suggested that mutations in spindle checkpoint genes may account for CIN. However, here we show that CIN cells do ...

background: contrast induced nephropathy (cin) is one of the most common complications after radiographic procedures using intravascular radiocontrast media. the aim of the current study was to assess the effect of atorvastatin on prevention of cin in patients undergoing coronary angiography. materials and methods: in a clinical trial study, 200 patients referred for angiography were randomly d...

OBJECTIVE This study aimed to estimate if risk factor profiles for histologically confirmed cervical intraepithelial neoplasia (CIN) 2 lesions differ from those for CIN 1 or 3. METHODS A total of 2,055 women positive for high-risk human papillomavirus, with a minimum of five cervical biopsies, were enrolled in the Shanxi Province Cervical Cancer Screening Study II. We evaluated risk factor pr...

The objective of this study was to determine if cinnamaldehyde (CIN) could be used to improve feed intake, digestion, and immune status in growing beef heifers fed high-concentrate diets. The experiment was designed as a 4 x 4 Latin square using 4 ruminally and duodenally cannulated beef heifers with 4 treatments: control (no CIN added), 400 mg/d of CIN (low), 800 mg/d of CIN (medium), and 1,60...

Chromosomal instability (CIN) refers to genomic instability in which cells have gained or lost chromosomes or chromosomal fragments. A high level of CIN is common in solid tumours and is associated with cancer drug resistance and poor prognosis. The impact of CIN-induced stress and the resulting cellular responses are only just beginning to emerge. Using proliferating tissue in Drosophila as a ...

Chromosomal instability (CIN), defined by an elevated frequency of the occurrence of novel chromosomal aberrations, is strongly implicated in the generation of aneuploidy, one of the hallmarks of human cancers. As for aneuploidy itself, the role of CIN in the evolution and progression of malignancy is a matter still open to debate. We investigated numerical as well as structural CIN in primary ...

Aim To identify the predictive factors and biomarkers in the progression of cervical precancer lesion or Cervical Intraepithelial Neoplasia (CIN). Methods The study was conducted from August 2007 to September 2008. Design of the study was case-control with stratifi cations of test dose response. The cases were patients with CIN. Control patients were non CIN patients. Bivariate analysis followe...

Conflicting data have been reported on the clinical significance of contrast-induced nephropathy after CT scan (CT-CIN). In addition, the epidemiologic characteristics and clinical outcomes of CT-CIN following proper prophylactic intervention remain elusive.We examined the incidence, risk factors, and outcomes of CT-CIN in stable chronic kidney disease (CKD) patients using data collected from o...