Natural monoglycerides of cinnamic, ferulic and p-coumaric acids were synthesized in good to high overall yields from isopropylidene glycerol via the Mitsunobu reaction and further deprotection of the corresponding acetonides with Amberlyst 15. The method avoids the need of protection of the phenolic hydroxyls. During the Mitsunobu esterifications a strong influence of the acid strength on the ...

(Phytochemistry, 26, 2418 (1987)) Acylated Luteolin Glucosides from Salix gitgiana. MIzuo MIzuNo*, MAsAyA KATo, MuNEKAzu IINuMA, TosHIyuKI TANAKA, ' ARIKA KIMuRA, HIRoyosHI OHAsHI, HIDEKI SAKAi Besides apigenin and luteolin 7-glucoside, four novel glucosides acylated with acetic, trans-cinnamic, P-coumaric and ferulic acids, respectively were isolated from the leaves of Salix gitgiana (Salicace...

The present manuscript reviews the findings of different research studies that evaluate use fungal solid-state (SSF) and submerged culture fermentation (SCF) with agro-industrial residues as substrates to enhance production polyphenols their possible uses food additives. Some (peels, pulps seeds) are an important source phenolic acids (p-coumaric, p-hydroxybenzoic, chlorogenic, cinnamic, feruli...

Cinnamic acid and its derivatives have shown a variety of pharmacologic properties. However, little is known about the antiglycation properties of cinnamic acid and its derivatives. The present study sought to characterize the protein glycation inhibitory activity of cinnamic acid and its derivatives in a bovine serum albumin (BSA)/fructose system. The results demonstrated that cinnamic acid an...

A series of fulvenes derived from isodicyclopentadiene has been prepared and their n.m.r. spectra studied. The simple low-field spectrum enabled immediate assignment of H a and both HY-ck. and HY-trass. The shifts are correlated with a-electron densities calculated for a model compound and the transmission of charge from the a-carbon to the five-membered ring w a s found to be between that for ...

OSW-1, isolated from the bulbs of Ornithogalum saundersiae Baker, is a steroidal saponin endowed with considerable antitumor properties. Biosynthesis of the 4-methoxybenzoyl group on the disaccharide moiety of OSW-1 is known to take place biochemically via the phenylpropanoid biosynthetic pathway, but molecular biological characterization of the related genes has been insufficient. Cinnamic aci...

We have investigated the anti-inflammatory effects of Cinnamomum cassia constituents (cinnamic aldehyde, cinnamic alcohol, cinnamic acid, and coumarin) using lipopolysaccharide (LPS)-stimulated mouse macrophage (RAW264.7) and carrageenan (Carr)-induced mouse paw edema model. When RAW264.7 macrophages were treated with cinnamic aldehyde together with LPS, a significant concentration-dependent in...

Trans-cinnamic acid and p-coumaric are valuable intermediates in the synthesis of flavonoids widely employed food, flavor pharmaceutical industries. These products can be produced by deamination L-phenylalanine L-tyrosine catalyzed phenylalanine ammonia lyase or tyrosine lyase. Phenylalanine ammonia-lyase (PAL, EC 4.3.1.5) from Rhodotorula glutinis do not exhibit strong substrate specificity co...