Correspondence: Judith A. Ferry, M.D., Department of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, USA. Telephone: 617-726-3978; Fax: 617-726-7474; e-mail: [email protected] Received January 13, 2006; accepted for publication February 22, 2006. ©AlphaMed Press 1083-7159/2006/$20.00/0 Abstract Burkitt’s lymphoma is a highly aggressive lymphoma identif...

: Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous group of non-Hodgkin's (NHL), characterized by poor outcome, accounting approximately for 10%-15% all non-Hodgkin in the western countries, and with higher prevalence Asia. Cyclin D1 immunoreactivity is characteristically seen mantle cell lymphoma. It also observed hairy leukemia, plasma myeloma proportion diffuse large B-cell lymp...

abstract background: primary cardiac lymphoma is extremely rare. case report: in this care report, we present the case of a 46-year-old man with primary cardiac lymphoma involving left atrium and interatrial septum, presenting as dyspnea palpitation and irregular heart beat. the diagnosis was obtained by transthoracic echocardiography and surgical biopsy with subxiphoid approach which revealed ...

Chromosomes were studied in 61 patients with differentiated B-cell malignancies including 21 with non-Hodgkin's lymphoma (NHL), three with hairy cell leukemia (HCL), eight with Waldenström's macroglobulinemia (WM), and 29 with plasma cell disorder. Chromosomally abnormal clones were identified in 35 of 61 patients studied: all with NHL, all with HCL, three of eight with WM, and eight of 29 with...

PURPOSE To investigate the activity of SAR3419, a novel humanized anti-CD19 antibody (huB4), conjugated to a cytotoxic maytansine derivative N(2)'-deacetyl-N(2)'-(4-mercapto-4-methyl-1-oxopentyl) maytansine, in preclinical xenograft models for non-Hodgkin's lymphoma. EXPERIMENTAL DESIGN Antitumor activity of SAR3419 was assessed as a single agent and in comparison with conventional therapies ...

Karyotype evolution of t(14;18)-positive lymphoma was studied in 13 Japanese patients. The extra 18q- chromosome, found in six of ten patients with complex karyotypes, was the most common change subsequent to a t(14;18)(q32;q21) chromosome translocation. The additional change was interpreted as being a duplication of an 18q- derived from a t(14;18). The six patients had transformed histology of...

A study of 260 patients with non-Hodgkin's lymphoma (NHL) who underwent bilateral bone marrow biopsy at initial diagnosis showed marrow disease in 99 (38%) cases. The highest incidence of disease (83%) was seen in small lymphocytic lymphoma (SLL) and the lowest (19%) in diffuse large cell lymphoma (DLCL). Among cases with positive marrows, disease was bilateral in all 15 cases of SLL but in onl...

background: various infectious agents like ebstein barr virus (ebv), htlv-1 and helicobacter pylori have known as etiologic factors in different sub-types of lymphoma. although hepatitis c virus (hcv) has not only been important for its hepatotropism and hepatitis development, but also in recent years its association with some forms of non- hodgkin’s lymphoma (nhl), especially b cell nhl, has r...