Human telomerase reverse transcriptase (hTERT) gene expression in resected specimens of oral squamous cell carcinoma (OSCC) and their surrounding tissue, either apparently normal or clearly histologically dysplastic, was evaluated by both real-time RT-PCR and immunohisto-chemical protein analyses. The expression level of hTERT in oral dysplasia and in OSCC was markedly higher than in normal tis...

In order to obtain more information on the pattern of CD11c-positivity in otherwise typical B-cell chronic lymphocytic leukemia (CLL), we analyzed immunological and clinico-pathological features of 99 such patients studied with two different monoclonal antibodies (MoAbs). Fifty-two out of 70 (74.2%) patients stained with IOM-11C MoAb and 3 out of 29 (10.3%) patients stained with Leu-M5 MoAb had...

Sepse é uma condição sistêmica que gera resposta inflamatória exacerbada nos pacientes, e mesmo com os avanços na saúde, ela ainda das principais causas de internação mortalidade em UTIs. O presente artigo tem como objetivo verificar a aplicabilidade dos marcadores dentro do manuseio clinico, identificar alterações biomarcadores ligados à sepse correlacionar bioquímicos hematológicos durante o ...

Odontogenic myxoma (OM) is a rare tumourarising in the jaws. It is considered to be derived from ectomesenchymal portion of tooth germ.They are slow growing, non-metastasizing, often asymptomatic with local aggressiveness due to its infiltrative nature and hence high recurrence rate, with a high incidence of occurrence in the mandible. Most frequently occurs in second to third decade of life, s...

Background: Diagnosing tuberculosis in children remains a challenge especially low-income countries. The aim of this study was to assess the performance scoring system combined chest x-ray images compared GeneXpert for diagnosis pediatric tuberculosis.Methods: A retrospective diagnostic accuracy carried out on hospitalized aged 0 14 years old, suspect department Tsaralalana mother child univers...

Introduction: Leprosy is a chronic, infectious disease caused by Mycobacterium leprae. It is classified into five groups based on clinical, histological, microbiological and immunological criteria (Ridley & Jopling Classification). However a great variation is seen in interpretation of clinical and histopathological examination of these lesions. The present research was taken to study the corre...

Onychomycosis is a common nail disorder. Far more than being a simple cosmetic problem, infected nail serves as a chronic reservoir, which can give rise to repeated mycotic infections. The study was undertaken to determine the various clinical patterns of onychomycosis. This prospective cross sectional study was conducted in clinically suspected patients of onychomycosis attending out patients ...

OBJECTIVE To determine the clinico-pathological and histological features of Chondroblastoma (CB). STUDY DESIGN Case series. PLACE AND DURATION OF STUDY The Aga Khan University Hospital, Karachi, from 2000 to 2013. METHODOLOGY The histological slides of all reported cases of CB were retrieved and reviewed for morphological features. Clinical features were noted from surgical pathology rep...

In this paper, we describe an analysis tool based on the statistical environment R, GridR, which allows using the collection of methodologies available as R packages in a grid environment. It provides the user with transparent and seamless access to large-scale distributed computational services and data repositories within the secure and reliable framework of a grid system. The aim of GridR, w...

INTRODUCTION Mucormycosis is life threatening infection rarely affecting musculoskeletal system and spinal involvement is extremely rare with only two cases reported in English literature. CASE REPORT We present this rare case of spondylodiscitis with lumbar vertebral osteomyelitis due to mucormycosis in a patient with chronic kidney disease on haemodialysis diagnosed by CT guided biopsy and ...