This is a report of an unusual case, where the patient used clitoral and/or vaginal masturbation and orgasm for treatment of migraine attack. While the non drug treatment was effective, she subsequently developed depression. The orgasm from masturbation, resulting in the rush of endorphins, probably relieved the migraine. However, as demonstrated in our patient, the patient also had sexual aver...

cultures are diBcult to define, but include rites of Introduction passage, blood sacrifices and cultural markings [4]. Ritualistic, childhood genital surgery has become popuThe prepuce is a common anatomical structure of the male [1] and female [2] external genitalia of all human lar in the last several thousand years, making the prepuce the most vilified normal anatomical structure and non-hum...

Abstract Introduction Clitoral adhesions occur when the clitoral prepuce adheres to glans clitoris. This can cause accumulation of desquamated epithelial cells under prepuce, resulting in formation smegmatic pseudocysts and keratin pearls. A pearl is a focus central keratinization within concentric layers squamous cells. Presence these firm, millimeter-sized masses lead irritation hypersensitiv...

OBJECTIVE To evaluate the prevalence and risk factors for unrecognized invasive carcinoma in a series of patients undergoing surgical excision after an office biopsy of vulvar high-grade squamous intraepithelial lesion (VHSIL). METHODS Two hundred and sixteen consecutive patients treated in a tertiary-level referral center for vulvar disease in north-western Italy were recruited. Patients' re...

Adrenogenital syndrome, or so called congenital adrenal hyperplasia, is caused by a congenital insufficiency of the enzyme 21-hydroxylase, which is responsible for converting cortisol into cholesterol. Because of virilizing effect of androgens overproduction girls develop clitoral hypertrophy and persistent urogenital sinus (common channel for urethra and vagina). Surgical treatment is recommen...

INTRODUCTION Vaginal sling procedures may have a negative effect on sexual function due to damage to vascular and/or neural genital structures. Even though autonomic innervation of the clitoris plays an important role in female sexual function, most studies on the neuroanatomy of the clitoris focus on the sensory function of the dorsal nerve of the clitoris (DNC). The autonomic and somatic path...