OBJECTIVE To evaluate the effectiveness and safety of pentoxyfylline in treatment of perniosis in comparison with prednisolone plus topical clobetasol ointment. METHODS This is an open comparative therapeutic trial conducted in the Department of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq between January and March 2008. Forty patients with perniosis were enrolled in this study, and ...

Due to the anti-inflammatory and vasodilator effects of topical corticosteroids, they help in treating atopic eczema, psoriasis, chronic hand localized vitiligo, among other dermatological diseases. Clobetasol propionate (CP) is most popular medication used treat plaque psoriasis. It has anti-inflammatory, antimitotic, antipruritic, immunosuppressive characteristics. The USFDA approved CP 0.025...

of lichen planus follicularis tumidus and Hashimoto’s thyroiditis. An Bras Dermatol. 2017;92(4):585-7. Mailing address: Hatice Kaya Ozden Kocaeli Derince Training and Research Hospital Dermatology Department 41900 Kocaeli / Turkey E-mail: [email protected] We observed a slightly itchy, tumid, violaceous plaque in our patient only in the left retroauricular region and classic lichen planus lesion...

Dapsone has been used successfully as adjuvant therapy for bullous pemphigoid (BP). The effectiveness of dapsone for this indication, however, remains controversial. We evaluated the effectiveness and adverse events of dapsone (1.0-1.5 mg/kg per day) in combination with oral methylprednisolone (tapering doses of 0.5 mg/kg per day) and topical clobetasol propionate (initially applied once daily ...

Background: Bullous pemphigoid (BP) is an antibody-mediated blistering disease predominantly affecting the elderly. Corticosteroids are mainstay of treatment but they have many side effects. Therefore, a novel highly necessary.. Objective: To explore effects autoantibodies on keratinocytes and to examine therapeutic potential agent, diacerein. Methods: Cultured HaCaT cells were treated with pur...

We herein report two cases of eosinophilic annular erythema in adults, which is rare. In both patients, lesions developed rapidly in few days and were located mainly on the trunk, buttocks, and extremities. Diagnosis was histopathological, with typical features including acute dermal inflammatory infiltrate with abundant eosinophils. One of the patients recurred after treatment on three occasio...

Acrodermatitis continua of Hallopeau (ACH) is considered as a localized form of pustularpsoriasis that is usually refractory to the treatment. The condition is characterized by sterile pustules, onychodystrophy, anonychia, and osteolysis of distal phalanges. The authors report a case of recalcitrant ACH who previously failed to topical corticosteroid, methotrexate, acitretin, and phototherapy a...