multidrug-resistant (mdr) and extensively drug-resistant (xdr) tuberculosis (tb) are increasing globally. treatment options for these patients are very limited. although treatment of these patients with standardized regimen is associated with high mortality and morbidity, rational usage of new drugs might be promising. in this study we will review epidemiology of xdr-tb and tdr-tb in iran and t...

background: candida parapsilosis is an emergent agent of invasive fungal infections. this yeast is one of the five most widespread yeasts concerned in invasive candidiasis. c. parapsilosis stands out as the second most common yeast species isolated from patients with bloodstream infections especially in neonates with catheter. recently several reports suggested that its reduced susceptibility t...

nosocomial infection caused by methicillin-resistant staphylococci poses a serious problem in many countries. the aim of this study was to rapidly and reliably detect methicillin-resistant-staphylococci in order to suggest appropriate therapy. the presence or absence of the methicillin-resistance gene in 115 clinical isolates of staphylococcus aureus and 50 isolates of coagulase negative staphy...

background vancomycin resistant isolates of enterococcous faecium (vre) have previously been reported from tehran hospitals. however, little data were available on the genetic heterogeneity of vre isolates among the iranian population. therefore the emergence of infections with the new clones of vre needs to be investigated. the drug resistance surveillance program at labbafinejad hospital has ...

conclusions although very rare, mdr miliary tb can be seen in immunocompetent subjects. we, thereby, emphasize that early recognition and initiation of treatment are associated with a significant improvement in outcomes. tuberculosis remains a serious worldwide health problem associated with high morbidity and mortality. case presentation our case was a young female patient with in vitro fertil...

conclusions the population structure of the a. baumannii isolates in our hospitals was genetically diverse. a significant association between xdr pattern and presence of class 1 integron (p < 0.001) was found indicating that many antibiotic resistance determinants are involved in development of xdr strains. materials and methods during a three-year study, clinical isolates of a. baumannii were ...

methicillin-resistant staphylococcus aureus (mrsa) is the main cause of hospital infection emerged over the last decades. rapid detection of mrsa is important for patient care and proper usage of infection control. detection of meca genes (encoding resistance to methicillin and other similar antibiotics) and nuc genes (encoding staphylococcal thermostable nuclease) by pcr method is now consider...

for many years , penicilline was the only drug of choice for treatment of gonorrhoeae, but the increased incidence of this disease in many parts of the world and the failure of penicilline-therapy against it has brought the theory of penicilline-resistant strains of gonococcus. on the other hand , the increased incidence of asymptomatic infection of gonorrhoeae especially in females has been co...

conclusions ethanol extracts of p. granatum (pericarp, leaves, flowers, seeds) have antibacterial effects against p. haemolytica which has shown resistance to all studied antibiotics. background continuous researches on drugs that solve the problem of growing number of resistant bacteria are important. objectives this research aims to investigate the effectiveness of anti-bacterial properties s...