The hematologic system encompasses blood and plasma volume, the constituents of plasma, and the formation and function of blood cellular components. Hemostasis involves mechanisms that result in the formation and removal of fibrin clots. Pregnancy and the neonatal period are associated with significant changes in these processes, increasing the risk for anemia and alterations in hemostasis such...

Hematologic complications of HIV disease are commonly encountered by physicians and other health-care workers caring for patients infected with this virus. Ineffective hematopoiesis, infiltrative diseases of the bone marrow, nutritional deficiencies, peripheral destruction of blood cells secondary to splenomegaly or immune dysregulation, and drug effects all contribute to the variety of hematol...

Objective: to analyze the epidemiological aspects and factors associated with survival of critically ill patients diagnosed Covid-19. Method: this is a non-concurrent cohort study information from 205 Covid-19 patients. Results: incidence lethality were, respectively, 60.3% 46.8%. The mean time was 21.8 days, lower were high score on Simplified Acute Physiology Score, shorter mechanical ventila...

BACKGROUND Post-tonsillectomy hemorrhage (PTH) has been reported in the literature as a serious complication after tonsillectomy that has high morbidity and can be life threatening. In cases of recurrent secondary PTH, one should consider coagulopathies as the hidden pathology. Factor XIII deficiency is very rare, suggested to be present 1 in 2 million people. Patients with undiagnosed factor X...

Background A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system. Methods Reference values for coagulation parameters from forty-three animals were calculated using data obtained from the ROTEM® delta hemostasis analyzer with the EXTEM test. Res...

Aspirin and nonaspirin nonsteroidal antiinflammatory drugs (NSAIDs) inhibit platelet cyclooxygenase, thereby blocking the formation of thromboxane A2. These drugs produce a systemic bleeding tendency by impairing thromboxane-dependent platelet aggregation and consequently prolonging the bleeding time. Aspirin exerts these effects by irreversibly blocking cyclooxygenase and, therefore, its actio...