The study included collecting 40 blood samples [18 females and 22 males] for patients with stroke, the results were compared control group healthy people that 50 [24 26 males], trace elements [zinc, copper, magnesium, manganese, iron, cobalt chromium] measured two groups. It was noted there a significant decrease in level of zinc, manganese chromium patient both sexes, while increase levels iro...

Zinc Oxide doped with chromium and cobalt, in form of powder with nanometer size has been prepared by typical solgel route, with assistance of microwave radiations. The as prepared material’s structure was characterized under XRays Diffraction(XRD) and Scherrer formula was used to find the crystal size. The materials also have been characterized under Scanning Electron Microscope(SEM) and Trans...

Water and sediment samples were collected from 20 location of the Buriganga river of Bangladesh during Summer and Winter 2009 to determine the spatial distribution, seasonal and temporal variation of different heavy metal contents. Sequential extraction procedure was employed in sediment samples for the geochemical partitioning of the metals. Total trace metal content in water and sediment samp...

The mold Neurospora crassa does not accumulate porphyrins in iron deficiency but instead accumulates the sideramine desferricoprogen. In iron deficiency there is an accumulation of &aminolevulinic acid and the d-aminolevulinic acid dehydratase level is very low. A similar situation exists in cobalt toxicity and zinc deficiency. The b-aminolevulinic acid synthetase and ferroprotoporphyrin chelat...

Native zinc/cobalt-containing ATP sulfurylase (ATPS; EC 2.7.7.4; MgATP:sulfate adenylyltransferase) from Desulfovibrio desulfuricans ATCC 27774 was purified to homogeneity and crystallized. The orthorhombic crystals diffracted to beyond 2.5 A resolution and the X-ray data collected should allow the determination of the structure of the zinc-bound form of this ATPS. Although previous biochemical...

Hemoglobin is composed of two pairs of globin chains to which are attached four iron-containing metalloporphyrins. Factors regulating hemoglobin synthesis include the availability of iron and the presence of heme. Heme production occurs by enzymatic synthesis and includes a step mediated by aminolevulinic acid dehydrase, which is zinc-dependent and, thus, susceptible to the toxic effects of oth...

Iron is an essential nutrient but in excess may damage cells by generating reactive oxygen species due to Fenton reaction or by substituting for other transition metals in essential proteins. The budding yeast Saccharomyces cerevisiae detoxifies cytosolic iron by storage in the vacuole. Deletion of CCC1, which encodes the vacuolar iron importer, results in high iron sensitivity due to increased...

Two classes of metal ion binding sites in horse liver alcohol dehydrogenase are distinguished by the observed rates of replacement of zinc by cobalt in acetate and in Z-(N-morpholine)-ethane sulfonic acid buffers. Hybrid enzymes containing both zinc and cobalt metal ions have been prepared and exhibit visible absorption maxima at 655 nm and 740 nm. Binding of azide, a substrate-competitive inhi...

BACKGROUND Improper waste disposal is responsible for the contamination of both surface and ground water resources. Heavy metals leached from improperly disposed solid waste constitute grave environmental and health hazards because of their toxic and persistent nature. There are thousands of open dumps in Nigeria one of which is the Enugu State Waste Management Authority dumpsite. METHOD Fort...