BACKGROUND Severe and fatal complications of toxoplasmosis urge development of effective vaccines against the disease. The current study was performed to evaluate cocktail DNA vaccine containing plasmids encoding GRA5, SAG1, and ROP2 genes of Toxoplasma gondii in BALB/c mice in Tarbiat Modares University in 2012. METHODS The plasmids containing complete GRA5, SAG1, and ROP2 genes were mass ex...

This paper is an attempt to address the problem of native language in a mixed voice environment. G- Cocktail would aid these applications identifying commands given Gujarati, even from stream. There are two phases G-cocktail first phase, it creates features after filtering voices and second trains classifies dataset. trained dataset helps recognizing new signal. The challenge training availabil...

Poor pharmacokinetics is one of the reasons for the withdrawal of drug candidates from clinical trials. There is an urgent need for investigating in vitro ADME (absorption, distribution, metabolism and excretion) properties and recognising unsuitable drug candidates as early as possible in the drug development process. Current throughput of in vitro ADME profiling is insufficient because effect...

Use of Bacteriophages as Antimicrobials Against Avian Pathogenic Escherichia coli Infections in Poultry: from Isolation to Therapeutic Evaluation The poultry industry is affected by huge economic losses due to APEC infections. Colibacillosis is a cause of increased mortality and morbidity, decreased productivity and carcass rejection. The application of phage therapy to the large food animal in...

Materials and Methods Formalin-fixed paraffin-embedded lung SqCC (n=137) and LADC (n=60) tissue microarrays were acquired. DSG3/p40 + Napsin A double stain cocktail (Biocare Medical, Concord, CA), TTF-1 [SPT24] and TTF-1 [8G7G3/1] antibody titers were optimized for IHC. SPT24 was optimally titered at 1:1200. The double stain antibody cocktail was detected by using a polymer double stain detecti...

Severe combined immunodeficient (SCID) mice injected intravenously with a human Burkitt’s lymphoma cell line (Daudi) develop disseminated lymphoma (SCID/Daudi), which is fatal in 100% of the mice. Early treatment of these mice with either an immunotoxin (IT) cocktail (consisting of anti-CD19-ricin A chain plus anti-CD=-ricin A chain) or chemotherapy significantly prolonged survival but w...

Severe combined immunodeficient (SCID) mice injected intravenously with a human Burkitt’s lymphoma cell line (Daudi) develop disseminated lymphoma (SCID/Daudi), which is fatal in 100% of the mice. Early treatment of these mice with either an immunotoxin (IT) cocktail (consisting of anti-CD19-ricin A chain plus anti-CD=-ricin A chain) or chemotherapy significantly prolonged survival but w...

Epithelial cells are important in the regeneration of oral mucosal tissue. The cell source is commonly derived from tissue biopsy, which obtained through surgery. Stem human exfoliated deciduous teeth (SHED) were demonstrated to differentiate into multiple types. As it can be readily available teeth, induced and become a potential epithelial for study. This study aims examine mixture growth fac...