Behavioral and psychological symptoms (BPSD) are now known to be frequently associated to cognitive and functional decline in Alzheimer's disease and related disorders. They are present since the early stages of the disease and have negative impact on the disease process. BPSD assessment is crucial in clinical practice and also in future clinical trials targeting disease-modifying therapies for...

PPA: Primary Progressive Aphasia; PIA: Progressive Ideomotor Apraxia; CPAP: Continuous Positive Airway Pressure; MoCA: Montreal Cognitive Assessment; MINI: Mini-International Neuropsychiatric Interview; WASI: Wechsler Abbreviated Scale of Intelligence; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status; DRS: Dementia Rating Scale TMT-A & B: Trail Making Test-A and B; GAD-...

PPA: Primary Progressive Aphasia; PIA: Progressive Ideomotor Apraxia; CPAP: Continuous Positive Airway Pressure; MoCA: Montreal Cognitive Assessment; MINI: Mini-International Neuropsychiatric Interview; WASI: Wechsler Abbreviated Scale of Intelligence; RBANS: Repeatable Battery for the Assessment of Neuropsychological Status; DRS: Dementia Rating Scale TMT-A & B: Trail Making Test-A and B; GAD-...

BACKGROUND We examined the discriminant validity of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) in detecting multiple-domain mild cognitive impairment (md-MCI) in a Chinese sub-sample drawn from elderly population-based study. METHODS This study included Chinese participants from the Epidemiology of Dementia in Singapore (EDIS) study aged ≥ 60 years w...

This study compared individual cognitive behavioral therapy (CBT) and a supportive child-centered therapy (CCT) for child anxiety disorders on rates of treatment response and recovery at posttreatment and 1-year follow-up, as well as on real-world measures of emotional functioning. Youth (N = 133; ages 9-14) with anxiety disorders (generalized, separation, and/or social anxiety) were randomized...

To date, there has not been a time-efficient and resource-conscious way to identify cognitive impairment in patients with substance use disorders (SUDs). In this study, we assessed the validity, accuracy, and clinical utility of a brief (10-min) screening instrument, the Montreal Cognitive Assessment (MoCA), in identifying cognitive impairment among patients with SUDs. The Neuropsychological As...

BACKGROUND/AIMS Performance on the Montreal Cognitive Assessment (MoCA) has been demonstrated to be dependent on the educational level. The purpose of this study was to identify how to best adjust MoCA scores and to identify MoCA items most sensitive to cognitive decline in incipient Alzheimer's disease (AD) in a Spanish-speaking population with varied levels of education. METHODS We analyzed...

BACKGROUND/AIMS Single, global or unitary, indicators of test diagnostic performance have intuitive appeal for clinicians. The Q* index, the point in receiver operating characteristic (ROC) curve space closest to the ideal top left-hand corner and where test sensitivity and specificity are equal, is one such measure. METHODS Datasets from four pragmatic accuracy studies which examined the Min...

Interpretation of cognitive test profiles is popular in school psychological training and practice but is not supported by research evidence. This special issue contains four studies that provide additional data regarding cognitive test profiles. Consistent with the largely negative research literature, detailed analysis found all four cognitive profile reports lacking reliability, validity, or...