The aim of the present study is to investigate the mechanisms of suppression of splenic natural killer (NK) cytotoxicity caused by cold stress, using 6-hydroxydopamine (6-OHDA) as chemical sympathectomy. The NK activity was measured by (51)chromium release assay. Central sympathectomy with intracerebroventricular (i.c.v.) injection of 6-OHDA reduced significantly the elevation of plasma cortico...

o bjectives: temporomandibular dysfunction (tmd) is a group of disorders in the facial region and temporomandibular joint (tmj). biomarkers are assumed to play a role in pain and early detection of destruction. the aim of this study was to compare the saliva and serum antioxidant levels in patients with tmd and healthy subjects. mat erials and methods : this case-control study was conducted on ...

Antioxidants are molecules that restrain the process of oxidation. Anti-mutagens are the medium to prevent any DNA transformation. Irreversible DNA damage is caused by mutagens and carcinogens. Defective metabolism occurs due to oxidative stress which can be avoided by antioxidants. The tumour causing ability of nitrosamines, which is commonly referred as chemical carcinogenesis, is been associ...

background: alzheimer’s disease (ad) is the most prevalent degenerative disorder of the brain among elderly individuals. many studies indicate that oxidative stress is an important pathogenic factor which involves oxidizing macromolecules such as dna, lipids, and proteins in ad. green tea is a rich source of antioxidant compounds that can remove radical oxygen species. the purpose of this study...

evidence acquisition literature searching for studies on female infertility and micronutrient intakes, published between january 1984 and november 2014, was performed using the pubmed and embase databases. the bibliographies of included studies were also searched for additional references. results about 100 articles were identified and after the elimination of irrelevant studies, 28 related stu...

Nephrotoxicity is the major limitation for the clinical use of cisplatin as an anti-tumoural drug. Intracellular effects of cisplatin cause tubular damage and tubular dysfunction with sodium, potassium, and magnesium wasting. Renoperotective strategies against cisplatin are classified on 8 targets: 1) Decrease of cisplatin uptake by renal cell, 2) Inhibition of cisplatin metabolism, 3) Blocking...

Transcriptome analysis of sugarcane hybrid CP72-1210 (cold susceptible) and Saccharum spontaneum TUS05-05 (cold tolerant) using Sugarcane Assembled Sequences (SAS) from SUCEST-FUN Database showed that a total of 35,340 and 34,698 SAS genes, respectively, were expressed before and after chilling stress. The analysis revealed that more than 600 genes are differentially expressed in each genotype ...

Aging is an extremely complex and multifactorial process that proceeds to the gradual dete‐ rioration in functions. It usually manifest after maturity and leads to disability and death. Traditionally researchers focused primarily on understanding how physiological functions decline with the increasing age; almost no research was dedicated to investigation of causes or methods of aging intervent...