UNLABELLED We present a new rodent SPECT system (U-SPECT-II) that enables molecular imaging of murine organs down to resolutions of less than half a millimeter and high-resolution total-body imaging. METHODS The U-SPECT-II is based on a triangular stationary detector set-up, an XYZ stage that moves the animal during scanning, and interchangeable cylindric collimators (each containing 75 pinho...

We present results from the flight of two prototype CZT detectors on a scientific balloon payload in September 2000. The first detector, referred to as “CZT1,” consisted of a 10 mm × 10 mm × 2 mm CZT crystal with a single gold planar electrode readout. This detector was shielded by a combination of a passive collimator in the front, giving a 40 degree field of view and surrounded by plastic sci...

In this paper we report the development of a prototype for a new kind of detector intended for scintimammography imaging. Traditional photon counting information is available; moreover digital words representing the amplitude of each event and suitable image elaboration methods significantly enhance detector capabilities. The prototype detector is composed of a collimator and 4 imaging modules....

Abstract We present the design and testing of a prototype in-plane echelle spectrograph based on an actively controlled fiber-fed double-pass design. This system aims to be small efficient with minimum number optical surfaces—currently collimator/camera lens, cross-dispersing prism, grating reflector send light detector. It is built from catalog components has dimensions approximately 20 × 30 c...

We implemented a fully-3D ordered subsets expectation maximization (OSEM) algorithm with compensation of attenuation, distance-dependent blurring (DDB) and sensitivity modeling for SPECT performed with cone-beam collimator (CBC). The experimentally obtained detector response to point sources across FOV was fitted to a twodimensional Gauss function with its width (FWHM) varied linearly with the ...

In this study we investigated the characteristics of a commercial ion chamber array and its performance in the verification of radiotherapy plans. The device was the 2D Array Seven29 model (PTW, Freiburg, Germany). This is a two-dimensional detector array with 729 ionization chambers uniformly arranged in a 27 x 27 matrix with an active area of 27 x 27 cm(2). The detector short-, medium- and lo...

Introduction: Sentinel lymph node biopsy (SLNB) is a standard surgical technique to identify sentinel lymph node (SLN) for the staging of early breast cancer. Nowadays, two methods are used for the identification of SLN: blue dye method aiding visually and radioactive dye using gamma detector. A wide range of gamma probe systems with different design and performance are used in...

A method for system matrix calculation in the case of iterative reconstruction algorithms in SPECT was implemented and tested. Due to a complex mathematical description of the geometry of the detector set-up, we developed a method for system matrix computation that is based on direct measurements of the detector response. In this approach, the influence of the acquisition equipment on the image...