For flexible sigmoidoscopy adequate preparation of the left side of the colon is essential. This is often achieved by administration of a phosphate enema by nursing staff in the endoscopy department. Patients may find the procedure embarrassing; it is also time consuming for the nurses. Home administered oral bowel preparation has been reported as safe, cheap, and effective, but no studies have...

Sodium phosphate (NaP) is a key component of the standard bowel preparation regimen for colon capsule endoscopy (CCE, PillCom® COLON2 Capsule Endoscopy: Medtronic, Minneapolis, MN, USA), particularly to cause excretion of the capsule endoscope while the battery is still functioning. Previous reports have demonstrated that other laxatives including polyethylene glycol and magnesium citrate were ...

Chitosan with excellent biodegradable and biocompatible characteristics has received attention as an oral drug delivery vehicle for controlled-release formulations. In this study an enteric-coated capsule containing theophylline-chitosan beads based on 23 factorial designs was prepared as a colon drug delivery system. The theophylline-chitosan gel beads were formulated by adding the drug-contai...

RK Colonoscopy is considered to be the gold standard of colon cancer screening. In fact, colonoscopy has been shown to reduce colon cancer mortality by approximately 50%. However, colonoscopy is not as effective on the right side of the colon as it is on the left side of the colon. Flat and serrated adenomas (precancerous conditions) are more common on the right side of the colon and harbor an ...

Objective : The aim of this study was to report the result of surgical treatment of volvulus of the sigmoid colon by colectomy in 2 phases.Material and methods: This is a descriptive and retrospective study during 5 years, led in the unit of digestive and general surgery of Aristide le Dantec Teaching Hospital (Dakar-Senegal). The criterion of inclusion was volvulus of the sigmoid colon treated...

One of the major goals of sensory neuroscience is to understand how an organism's perceptual abilities relate to the underlying physiology. To this end, we derived equations to estimate the best possible psychophysical discrimination performance, given the properties of the neurons carrying the sensory code.We set up a generic sensory coding model with neurons characterized by their tuning func...

Dysplasia represents a preneoplastic status in multistep colon carcinogenesis. Whereas laborious preparation of thin sections is required for its diagnosis, we here show that newly defined aberrant crypt foci (ACF) simply mark the majority of the dysplasia on the whole colon. Specifically, decoloring of the azoxymethane-treated rat colon after scoring classical ACF (cACF) resulted in visualizat...

GOALS We sought to determine if providers who have higher standards for optimal bowel preparation might be more fastidious in their examination of the colon and, therefore, have higher adenoma detection rates (ADRs). BACKGROUND ADRs are a reliable and objective marker of colonoscopy performance. Suboptimal bowel preparation impacts upon adenoma detection; however, physicians have varying stan...

Slim K, Vicaut E, Panis Y, et al. Meta-analysis of randomized clinical trials of colorectal surgery with or without mechanical bowel preparation. Br J Surg 2004;91:1125–30. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...

Anal cancer is a rare malignancy of the distal gastrointestinal tract, often associated with human papillomavirus, most common sexually transmitted infection worldwide. Currently available screening methods for anal intraepithelial neoplasia, precursor cancer, combine Papanicolaou cytology and high resolution anoscopy biopsy suspicious lesions. It well known that canal an area examined by proct...