To combine or not to combine? Though not a question of the same gravity as the Shakespeare’s to be or not to be, it is examined in this paper in the context of a hybrid neuro-fuzzy pattern classifier design process. A general fuzzy min-max neural network with its basic learning procedure is used within six different algorithm independent learning schemes. Various versions of cross-validation, r...

To combine or not to combine? This very important question is examined in this paper in the context of a hybrid neuro-fuzzy pattern classi(er design process. A general fuzzy min–max neural network with its basic learning procedure is used within (ve di3erent algorithm-independent learning schemes. Various versions of cross-validation and resampling techniques, leading to generation of a single ...

Due to the weakness of single methods their integration into hybrids is intensively researched in recent years. Most of these approaches use the static approach which is not successful in every situation therefore we build Multimethod approach that dynamically combines different machine learning methods following the assumption that only the synergetic combination of single models can unleash t...

Introduction The goal of this study is to find an alternate therapy for osteosarcoma (OS) lung metastasis. Previously we showed that NK cell therapy significantly decreased OS lung metastasis in a mouse model; however, the therapy was not effective enough to cure OS lung metastasis. To augment the NK cell therapy, we elected to combine it with entinostat, an HDAC inhibitor. Studies have shown t...

workplace factors such as sound must have the minimum impact on the operators of combine harvester, so that they can guide and control many functions of the combine. in this study, some factors affecting the noise generated by two combine harvesters john deere 1055 and sampo 3065 were evaluated. research factors were engine speed, gear ratios, type of operation and microphone distance. the resu...

Wheat is one of the important food staff in consumption pattern of each country. More than 50 % of human energy is supplied from bread in the developing country. Combine losses is less than 2-3% in developed countries, while in developing country is about 15-20% in different regions and circumstances of harvesting seasons and field conditions. In this research project that effect of combine typ...

Abstract Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since the response to treatment is variable, biomarkers urgently needed identify who may benefit from such therapy. Here, we combine single-cell RNA-sequencing and multiparameter flow cytometry assess changes in circulating CD8 + T cells 28 melanoma starting anti-PD-1 therapy, followed 6 months: 17 re...