background: umbilical cord blood (ucb) is an alternative source of hematopoietic stem cell transplantation (hsct), used in leukemia treatment. cd26+ cells, a fraction of cd34 positive cells, are a major population of ucb cells which negatively regulate the in vivo homing and engraftment of hscs. cd26 is highly expressed in various cells such as hscs, immune cells, fibroblasts, and epithelial ce...

human umbilical cord matrix (hucm) is considered as a promising source of mesenchymal stem cells (mscs) due to several advantages over other tissues. the potential of neural differentiation of hucm-mscs is of great interest in the context of treating neurodegenerative diseases. in recent years, considerable efforts have been made to establish in vitro conditions for improving the differentiatio...

Tumors of the umbilical cord are rare anomalies and should be considered when using prenatal ultrasound for detection of cystic lesions. Differential diagnosis of umbilical cord tumors should comprise umbilical cord teratoma, hemangioma and angiomyxoma. It can also be an umbilical cord polyp, umbilical cord cyst, hernia into the cord and omphalocele, which are mostly isolated findings, except o...

Trifunctional protein deficiency/Long-chain hydroxyacyl-CoA dehydrogenase deficiency (LCHAD/TFP) deficiency is a disorder of fatty acid oxidation and ketogenesis. Severe neonatal lactic acidosis, cardiomyopathy, and hepatic dysfunction are caused by the accumulation of toxic long-chain acylcarnitines. The feasibility of umbilical cord blood use in screening for acylcarnitine analysis and free c...

total serum copper levels of 70 pregnant women hospitalized for delivery at misaghieh (private), 90 at farah (public) maternity hospitals immediately after delivery and 27 non-pregnant women (control) were measured. the copper level in the blood serum of umbilical cord of the newborn infants was also determined. the copper levels were significantly elevated in both pregnant groups as compared t...

Uterine prolapsed is a rare condition occurs during pregnancy and lead to many complications. Usually conservative treatment approached to use a vaginal pessary accompanied with bed rest. This current case exhibited obvious role of a vaginal pessary in restoring the prolapsed organ till the time of labor and may expect delivery at home. When studying the style of labor, Gynecologist should bear...

We report a rare case of an umbilical cord hemangioma. The umbilical cord consisted of Capillaries and cavernous blood vessels and the hemangioma stressed umbilical arteries and vein. At 40 weeks of gestation, it resulted in intrauterine death of the fetus. Microscopically, there were lots of vessels with various thicknesses in the umbilical cord. Autopsy shows evidences of smothering. These fi...

Background: Abnormal umbilical cord pH can be indicated a distress imposed of newborn and can also be useful in determining the prognosis of the newborn. There are different views about the effect of the neonatal delivery method on the blood gas analysis of the umbilical artery. This study aimed to determine the effect of the method of delivery on umbilical artery pH. Methods: In this Cross ...

BACKGROUND In an era increasingly focused on quality improvement and cost containment, more emphasis is being placed on wiser utilization of medical care resources. One underutilized resource in early neonatal care is umbilical cord blood. FINDINGS Umbilical cord blood can be utilized for admission laboratory studies in neonates thereby avoiding a significant phlebotomy event in the first min...