Malignant gliomas are the most common malignant tumors in the central nervous system (CNS). Up to date, the prognosis of glioma is still very poor, effective therapy with less side-effect is very necessary. Herein, we identify a compound named as "331" selectively induced cell death in glioma cells but not in astrocytes. Compound 331 upregulated miR-494 and downregulated CDC20 in glioma cells b...

We employ first-principles density functional theory calculations to study the surface reconstruction, energetic stability, and electronic structure of diamond C(331) surface. Spontaneous formation of graphene-like stripes on the reconstructed surface is found to occur as the surface terrace C atoms transform from sp3 to sp2 hybridization upon structural relaxation. The comparison of the calcul...

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1Environmental Biofunction Division, National Institute for Agro–Environmental Sciences, 3–1–3 Kannondai, Tsukuba, Ibaraki 305–8604, Japan; 2Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) Hokkaido, 2–17–2–1 Tsukisamu-higashi, Toyohira-ku, Sapporo, Hokkaido 062–8517, Japan; 3Research Institute for Environmental Management Technology, AIS...

A mechanism for generating small tree-level Majorana mass for neu-trinos is implemented in the 331 Model. No additional fermions or scalars need to be added, and no mass scale greater than a few TeV is invoked.

On the biotransformation of phenol and monofluorophenols by the cultured cells of Eucalyptus perriniana, phenyl and fluorophenyl b-D-glucosides were isolated after a 1-h incubation. Especially, the yield of 2-fluorophenol is higher than those of the other substrates, i.e., phenol, 3and 4-fluorophenols. These results indicated that E. perriniana cells selectively glycosylate the hydroxyl group o...