The true incidence of congenital deformities of the upper airway is not known for certain, but van den Broek and Brinkman (1979) quoted an incidence for congenital laryngeal defects of between 1:10.000 and 1:50.000 births. Of 219 children with stridor who underwent endoscopic examination, Holinger (1980) found 81% to have evidence of congenital abnormalities of the larynx, trachea or bronchi. O...

ADDRESS: (D.C.) 300 Longwood Avenue, Boston 15, Massachusetts. -1 JfOST, if not all, of congenital metabolic lvi disease may be attributed to abnormalities in protein synthesis. An error in protein synthesis can result in at least two basic types of disturbance-an actual deficit of a specific protein, or the production of abnormal forms of that protein. Because of the wide variety of functions ...

OBJECTIVE To study the human teratogenic potential of tetanus vaccination during pregnancy. METHODS Pair analysis of cases with congenital abnormalities and matched healthy controls was performed in the large population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1994. RESULTS Of 35 727 pregnant women who had babies without any defects in the s...

The increase in number of food-producing animals each year implies that even small prevalences of congenital anomalies in these ruminant species are still reflected in a significant number of affected animals born each year. It takes a specific investigation to show the true incidence of such congenital abnormalities. This article discusses recent research into several conditions to demonstrate...

Background: Common types of Congenital penile anomalies (CPA) in children are; Hypospadias, Penile chordee, Micropenis, Hidden penis, Ambigous genitalia, Apenia and Unspecified genital or anomalies. Aim & objectives: The goal the work was to assess prevalence abnormalities prepubertal children. Subjects methods: research carried out outstudied case clinics Al-Azher University hospitals, on ...

OBJECTIVE To determine the accuracy of ultrasound in the diagnosis of congenital abnormalities at the Aga Khan University Hospital, Karachi. METHODS The data of congenital abnormalities was obtained from the obstetrical database and medical records of all cases complicated by congenital abnormalities, delivering from January 2001 to December 2003 and was reviewed. Antenatal ultrasounds had be...

BACKGROUND There is a strong maternal parent-of-origin effect in determining susceptibility to multiple sclerosis (MS). One hypothesis is that an abnormal intrauterine milieu leading to impaired fetal development could plausibly also result in increased susceptibility to MS. A possible marker for this intrauterine insult is the presence of a non-fatal congenital anomaly. METHODS We investigat...

A newborn infant was referred to the Department of Diagnostic Radiology, Princess Margaret Hospital, for further assessment for renal abnormalities detected by antenatal ultrasonography. Postnatal ultrasonography showed a cluster of noncommunicating cysts of varying sizes in the left renal fossa (Fig 1). The largest cyst was peripherally located. No normal renal parenchyma was detected in the l...

GROSS abnormalities are fortunately not common. Murphy (1940) in.Philadelphia found that approximately 47 individuals possessing congenital malformations were born alive or dead per 10,000 live births. About one-quarter of these were reported as stillbirthls. His data was collected mainly from death certificates and included only the grosser defects. Malpas (1937) recorded 294 cases in 13,964 c...

OBJECTIVE To study the effect of periconceptional multivitamin supplementation on neural tube defects and other congenital abnormality entities. DESIGN Randomised controlled trial of supplementation with multivitamins and trace elements. SETTING Hungarian family planning programme. SUBJECTS 4156 pregnancies with known outcome and 3713 infants evaluated in the eighth month of life. INTER...