Rubella, also known as German measles or three-day measles, is a self-limited, mild viral illness that poses little danger to children or adults. For the developing fetus, however, infection with rubella virus is a grave threat, capable of inducing severe anomalies and permanent disability. Despite widespread vaccination programs, populations of susceptible individuals persist, among them women...

Congenital malformations affect approximately 2-3% of all live births every year (Whiteman et al, 1994; Atlas et al, 1985). Congenital brain anomalies, whether they are isolated (single) or part of syndromes, are a common cause of medical intervention, long-term illness, and death. The neonatologist or perinatologist often is the first person to identify necessary evaluations and management and...

INTRODUCTION Congenital heart defects are the most common abnormalities in neonatal age. Congenital heart defects occur with a frequency of 3-12/1000 births. A special group is constituted by children with hypoplastic left heart syndrome because their treatment is extremely complex, requiring three-stage surgery and the involvement of various specialists. MATERIAL AND METHODS We analysed 100 ...

Primary central nervous system (CNS) lymphoma is a non-Hodgkin's lymphoma that arises within and is restricted to the nervous system. It usually presents as a brain tumor, but may also involve the leptomeninges, eyes, spinal cord, or any combination of these sites [1]. Formerly, the disease was rare, representing less than 1% of all intracranial tumors, but since 1974 there has been at least a ...

BACKGROUND Congenital thrombotic thrombocytopenic purpura (TTP), also known as Upshaw-Schulman Syndrome is a rare inherited deficiency of ADAMTS13. Unlike the more common acquired TTP which is characterized by an acquired inhibitor of ADAMTS13, patients with congenital TTP have an absolute deficiency of ADAMTS13 without an inhibitor. Congenital TTP generally presents in infancy with repeat epis...

OBJECTIVE Investigate support for the transactional stress and coping model for mothers of children with congenital heart defects, in accounting for the variance in maternal adjustment. METHODS Participants were 52 mothers of children recruited from a university medical center. Measures included illness variables, cognitive processes (i.e., appraisals of stress, expectations, methods of copin...

By CLA1 E N. SHUMWAY, ,JR. AND GF 1t. L1 \IILLE1t T lIE “HE 1oL TIc-[I F I1’ $YNI)ROME” is the tiarne suggested by Gasser et a!.’ for an illness of unknown etiology (haracterized by hemo1yti anemia, t hromhoeyt opeilia ai id renal in uffieietwy . Five rapidly fatal a e orcurring iii Childhood were de ciibed by these authors. Rerently A1li on2 (Ie 4(’rihed six infants with sii ilar (lilIi(al fin...

A single-stranded RNA virus of the Flaviviridae family, Zika is mainly spread by Aedes mosquitoes. infection was originally thought to be a mild and self-limiting illness when it first discovered in Uganda 1947. Infection pregnant women, causes serious congenital abnormalities, including microcephaly, condition marked an abnormally small head brain size, only 2015 as result significant outbreak...