Understanding the molecular and biochemical basis of cellular growth and division involves the investigation of regulatory events that most often occur in a cell-cycle phase-dependent fashion. Studies examining cell-cycle regulatory mechanisms and progression invariably require cell-cycle synchronization of cell populations. Thus, many methods have been established to synchronize cells at speci...

The high prevalence of contact dermatitis means that this common medical problem has considerable personal, societal, and economic impact. Clinical and epidemiologic research is needed if we are to shed light on the real situation of contact dermatitis in Spain. In this article we will look at epidemiologic research from a practical point of view and analyze the role of the dermatologist in pla...

These guidelines for management of contact dermatitis have been prepared for dermatologists on behalf of the British Association of Dermatologists. They present evidence-based guidance for investigation and treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, including details of relevant epidemiological aspects, diagnosis and invest...

Brian Stramer completed his undergraduate degree at the University of Rochester in Rochester, NY, and then moved to pursue his PhD at Tufts University in Boston, MA. He then crossed the Atlantic to work in the laboratory of Paul Martin as a US/UK Royal Society Fellow at the University of Bristol, UK. Before becoming a lecturer and a group leader at King's College London in 2008, Brian was also ...

We use the Ozsváth–Szabó contact invariant to produce examples of strongly symplectically fillable contact 3–manifolds which are not Stein fillable. AMS Classification numbers Primary: 57R17 Secondary: 57R57

BACKGROUND There are no studies on contact allergy in patients with prurigo. With itch being important in the pathophysiology of prurigo diseases and being a symptom of allergic contact dermatitis, we aimed to investigate contact allergy in patients suffering from prurigo. OBJECTIVES Exploratory analysis of patch test results in prurigo patients. MATERIALS AND METHODS A retrospective analys...

Objectives To describe the past 20 years' correction modalities for keratoconus and their visual outcomes and possible complications. Methods A review of the published literature related to the visual outcomes and possible complications in the context of keratoconus management using nonsurgical procedures for the last 20 years (glasses and contact lenses) was performed. Original articles that...

BACKGROUND Isolated cases of allergic contact dermatitis, gingivitis and stomatitis caused by beryllium have been previously reported. We have been able to study a series of 12 patients with patch test reactions to beryllium chloride. OBJECTIVES The study was aimed at defining the clinical and patch testing characteristics in this group of patients, and determining whether some were delayed e...

AIM Although 1 week of continuous wearing time (CWT) is recommended for extended wear soft contact lenses (EWSCL), there have been few studies concerning the appropriateness of this or other CWTs. The current study was undertaken to examine the effect of various CWTs on the cornea by observing the corneal epithelium. METHODS Specular microscopy was used to evaluate corneal epithelial changes ...

OBJECTIVE Demonstrate that successful soft contact lens wearers using competitive multipurpose solutions report improvement in comfort with OPTI-FREE((R)) RepleniSH((R)) Multi-Purpose Disinfecting Solution (MPDS). METHODS This 30-day, multicentered, open-label study enrolled 109 eligible soft contact lens wearers using COMPLETE((R)) Multi-Purpose Solution (MPS) Easy Rub((R)) or ReNu MultiPlus...