نتایج جستجو برای: contrastagent hyperthermia

تعداد نتایج: 9222  

Journal: :International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2012
Astrid Gasselhuber Matthew R Dreher Ari Partanen Pavel S Yarmolenko David Woods Bradford J Wood Dieter Haemmerich

PURPOSE To develop and validate a computational model that simulates (1) tissue heating with high intensity focused ultrasound (HIFU), and (2) resulting hyperthermia-mediated drug delivery from temperature-sensitive liposomes (TSL). MATERIALS AND METHODS HIFU heating in tissue was simulated using a heat transfer model based on the bioheat equation, including heat-induced cessation of perfusio...

Journal: :Journal of the Chinese Medical Association : JCMA 2007
Shu-Chia Hsu Wei-Tai Huang Huei-Ming Yeh Allen Yi-Jer Hsieh

Malignant hyperthermia is a rare anesthetic-related disorder. We present a case with unusual presentation. A boy aged 3 years and 9 months who was scheduled for Hotz's operation presented normally before the operation. Anesthesia was induced by atropine, thiopental and sevoflurane. Trachea intubation was facilitated by succinylcholine. Jaw stiffness was first noted although trachea was intubate...

Journal: :Current opinion in investigational drugs 2009
Joseph J Skitzki Elizabeth A Repasky Sharon S Evans

The use of hyperthermia as an adjunct to cancer immunotherapy is supported by an increasing number of research data. Both preclinical and clinical data results have demonstrated improved antitumor immune responses with the addition of mild hyperthermia. The molecular mechanisms responsible for the improved immune reactivity observed in the presence of hyperthermia include the generation of Hsps...

2005
Jennifer L. Phillips

Introduction The human body naturally uses heat to fight disease. For example, viruses and bacteria proliferate at normal body temperatures, so the body instinctively defends itself by increasing its temperature several degrees to slow the rapid multiplication of such disease-causing agents. This phenomenon, commonly called a fever, gives the body an advantage while fighting the infection. Feve...

Journal: :Nanoscale 2014
Aziliz Hervault Nguyen Th Kim Thanh

Magnetic nanoparticles have been widely investigated for their great potential as mediators of heat for localised hyperthermia therapy. Nanocarriers have also attracted increasing attention due to the possibility of delivering drugs at specific locations, therefore limiting systematic effects. The enhancement of the anti-cancer effect of chemotherapy with application of concurrent hyperthermia ...

Journal: :British journal of anaesthesia 2015
P M Hopkins H Rüffert M M Snoeck T Girard K P E Glahn F R Ellis C R Müller A Urwyler

It is 30 yr since the British Journal of Anaesthesia published the first consensus protocol for the laboratory diagnosis of malignant hyperthermia susceptibility from the European Malignant Hyperthermia Group. This has subsequently been used in more than 10 000 individuals worldwide to inform use of anaesthetic drugs in these patients with increased risk of developing malignant hyperthermia dur...

Journal: :Cancer research 1988
G G Jonsson L Menard E L Jacobson G G Poirier M K Jacobson

The effects of supranormal temperature on the activity of poly(ADP-ribose) glycohydrolase were studied by assaying the enzyme in cell extracts derived from cells subjected to hyperthermia and comparing with extracts that were heated in vitro. The enzyme activity was reduced by both hyperthermic treatment of cells and by heating of cell extracts; however greater reductions were observed when int...

Journal: : 2023

The objective – to summarize the current literature data on etiology, pathogenesis, diagnosis and treatment of malignant hyperthermia. search analysis hyperthermia in medical information systems PubMed, Сochrane librarу, Cyberleninka for last 10 years was performed with using keywords: «malignant hyperthermia», «dantrolene», «general anesthesia», «succinylcholine», «inhalation anesthetics». cri...

Ali Zarrabi Alireza Amouheidari Hamid Fakhimikabir Mohamad Bagher Tavakoli Soheila Rahgozar

Introduction: The objective of this work was to investigate the therapeutic effect of a combination of hyperthermia at 43oC exposured for 20, 40, 60 min with 6MeV electron beams at different radiation doses (2, 4, 6 Gy) compared to radiation alone.   Materials and Methods: In this in vitro study, HeLa cells were exposed to either: 6MeV electron beams at diffe...

Journal: :Journal of basic and clinical medicine 2012
Renshu Zhang Yanfei Zhou Paul C Wang Rajagopalan Sridhar

BACKGROUND Hyperthermia is used in combination with radiotherapy and/or chemotherapy in the treatment of various types of cancer. Currently, the tumor cell response to hyperthermia is determined largely based on the size reduction of tumor mass, which is insensitive. METHODS We tested the feasibility of bioluminescent imaging (BLI) in evaluation of the tumor cell response to hyperthermia by e...

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