Understanding infertility and sterility requires knowledge of the molecular mechanisms underlying sexual reproduction. We have found that male mice deficient for the gene encoding the protease inhibitor protease nexin-1 (PN-1) show a marked impairment in fertility from the onset of sexual maturity. Absence of PN-1 results in altered semen protein composition, which leads to inadequate semen coa...

today, enterprise architecture(ea) is one of the most important it solutions for business and it strategic alignment and also it is so supportive and effective tool for organizing and managing complicated information system in dynamic organization environment. due to efficient enterprise architecture management the organization can obtain the ea valuable benefits. ea maturity assessment is a he...

Background The utilization of immature oocytes derived from stimulated cycles could be of great importance, specially for urgent fertility preservation cases. The aim of the current study was to determine whether in-vitro maturation is more successful before or after the vitrification of these oocytes. MaterialsAndMethods The study was performed in a private IVF center. 318 germinal vesicle (GV...

Strategic alignment focuses on the activities that management performs to achieve cohesive goals across the IT (Information Technology) and other functional organizations (e.g., finance, marketing, H/R, manufacturing). Therefore, alignment addresses both how IT is in harmony with the business, and how the business should, or could be in harmony with IT. Alignment evolves into a relationship whe...

the bone is “fractured” or “broken”. While orthopaedic surgeons consider these terms synonymous, patients appear tocomprehend the terms as having different meanings. Given the commonality of this frequently posed question, it may beimportant for providers to assess patients’ level of understanding in order to provide optimal care. The purpose of thisstudy is to evaluate patients’ comprehension ...

Copulation normally culminates with two physiologically distinct events known as emission and ejlzctllafion.3~ 3o Emission is the release of sperm and accessory gland fluids into the pelvic urethra. Ejacdafion is the forceful expulsion of the combined fluids (i.e., semen) from the urethra. The associated perceptual-cognitive event called ovgrrsm in humans has not been characterized in nonhuman ...

Our understanding of how male seminal fluid proteins (SFPs) influence the outcome of copulation in a wide range of insect taxa has been fueled primarily by studies of Drosophila (1). SFPs are known to localize, after copulation, to specific regions of the female reproductive tract and nervous system. Manipulative studies revealed that these proteins control a number of postcopulatory processes,...