in the asemi-gawa area of intermediate high-pressure and low-temperature sanbagawa metamorphic belt in central shikoku, japan, piemontite-quartz schists are common in which cation exchange between piemontite and garnet has been studied. piemontite in contact with garnet usually contains two zones in which core is enriched in mn3+ and surrounded by a rim rich in fe3+. garnet is ca-fe-bearing spe...

RESULTS. In normal eyes, labeling for aB-crystallin occurred in the subendothelial region of Schlemm's canal and outer corneoscleral regions, whereas TIGR labeling was found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, labeling for aB-crystallin and TIGR occurred in more regions of the meshwork and appeared more intense tha...

The design and use of a new device for obtaining corneoscleral buttons for storage and corneal discs for keratoplasty from neonatal and adult donor eyes is described. The device is simple to use and eliminates most of the difficulties in handling infant donor eyes. It thus minimises the risk of damage to the corneal endothelium and the formation of stretch striae, which reduce the quality of th...

Figure 1 A, Slightly raised and somewhat irregular plaque with well-deined borders, and with a clear reduction in hair follicle density. B, Well-deined, slightly yellowish papule measuring 4 mm in diameter on the medial third of the right upper eyelid, and a translucent, yellowish-pink plaque with supericial telangiectasia extending across the corneoscleral junction. A. Elguezabal,a,* P. Turéga...

Rab3 interacting molecules (RIMs) are evolutionarily conserved scaffolding proteins that are located at presynaptic active zones. In the mammalian nervous system, RIMs have two major activities that contribute to the fidelity of baseline synaptic transmission: they concentrate calcium channels at the active zone and facilitate synaptic vesicle docking/priming. Here we confirm that RIM has an ev...

Synaptic communication requires the controlled release of synaptic vesicles from presynaptic axon terminals. Release efficacy is regulated by the many proteins that comprise the presynaptic release apparatus, including Ca(2+) channels and proteins that influence Ca(2+) channel accumulation at release sites. Here we identify Drosophila RIM (Rab3 interacting molecule) and demonstrate that it loca...

We report that herpes simplex virus type 1 (HSV-1) infection leads to the recruitment of protein kinase C (PKC) to the nuclear rim. In HEp-2 cells, PKC recruitment to the nuclear rim was initiated between 8 h and 12 h postinfection. PKCdelta, a proapoptotic kinase, was completely recruited to the nuclear rim upon infection with HSV-1. PKCalpha was less dramatically relocalized mostly at the nuc...

This study compiled a wide range of modern and historic geospatial datasets to examine ecological and geomorphic change at Diego Garcia Atoll across a 38-year period (1967–2005). This remarkable collection of spatially referenced information offered an opportunity to advance our understanding of the nature and extent of environmental change that has taken place with the construction of the mili...

In this paper, given a knot K , for any integer m we construct a new surface ΣK(m) from a smoothly embedded surface Σ in a smooth 4–manifold X by performing a surgery on Σ . This surgery is based on a modification of the ‘rim surgery’ which was introduced by Fintushel and Stern, by doing additional twist spinning. We investigate the diffeomorphism type and the homeomorphism type of (X,Σ) after ...