background abnormalities in the velocity and pattern of myocardial shortening on tissue doppler imaging (tdi) have been proposed to aid in the noninvasive diagnosis of coronary artery disease (cad). objectives we investigated the diagnostic value of post-systolic shortening (pss), a delayed ejection velocity of the myocardium after the closure of the aortic valve, on tdi in the diagnosis of cad...

background coronary artery disease (cad) is the most common cause of death worldwide. mef2a directly regulates target genes in the process of muscle development. this gene product is a transcription factor. mef2a protein in homodimer or heterodimer forms binds to a/t-rich cis elements with conserved sequence in promoter, regulator, and enhancer of many genes, which are determining in evolution ...

several epidemiological studies have reported that passive smoking (ps) is a public health hazard and perhaps increases the risk of heart disease. this study evaluated the relationship between female coronary heart disease and ps among married women who described themselves as non-smokers in an area of south-east iran. using household exposure to tobacco smoke as an estimate of ps, a hospitalba...

Introduction: Coronary artery disease is the most common type of cardiovascular disease. Despite the increasing number of patients with coronary artery disease, the lived experiences of these patients have remained unknown. The purpose of the study was to understand the lived experiences of elderly patients with coronary artery disease. Methods: This qualitative research was conducted usin...

objective vitamin e is a major lipid-soluble antioxidant. it has been demonstrated that vitamin e supplementation has a beneficial effect against coronary heart disease (chd). this study to investigate the effects of coronary risk factors on serum vitamin e status in patients with dyslipidaemia. materials and methods this tertiary care hospital; case - control study was comprised 237 dyslipidae...

percutaneous coronary angioplasty (ptca) of a coronary stenosis without documented ischemia at noninvasive stress testing is often performed, but its benefit is unproven. coronary pressure– derived fractional flow reserve (ffr) is an invasive index of stenosis severity defined as the ratio of maximal blood pressure in a stenotic vessel to the normal maximal pressure in the same vessel. ffr is a...

background: dyslipidemia is considered an independent risk factor for coronary heart disease (chd). in the present study, we examined lipid profiles and paraoxonase 1 (pon1) activity and atherogenic indexes status and the relationship of pon1 activity by high-density lipoprotein (hdl) and atherogenic indexes in chd patients and healthy people. methods: the aim of the study was to compare pon1, ...

conclusion we conclude that coronary calcium scoring provided useful information in the management of patients. in cacs less than 100, it has a npv of 87% in excluding significant stenosis in patients with the risk of cad but it does not have enough diagnostic accuracy for surely excluding coronary stenosis, so we should perform a combination of cacs and coronary ct angiography for patients. re...