Using intravenous sodium warfarin, rabbits were rendered hypoprothrombinemic and subjected to two intravenous injections of Shear's polysaccharide. None of the 9 animals surviving the required period of time developed bilateral renal cortical necrosis or histologic thrombi in the kidney, liver, spleen, or lungs. In a control group of 7 animals treated only with endotoxin, 6 developed bilateral ...

A 10-year-old male presented with vision loss and behavioral changes. He had midpoint pupils with no reaction to light and normal funduscopic examination. Cranial magnetic resonance imaging revealed bilateral cortical lesions at parieto-occipital lobes. Elevated measles antibody titers in the cerebrospinal fluid confirmed the diagnosis of subacute sclerosing panencephalitis. Despite oral inosip...

A pathophysiological chain reaction at the origin of neurogenic pain. It consists of: 1) a reduction of excitatory inputs onto thalamic cells, which results in cell membrane hyperpolarization, 2) the production of low-threshold calcium spike bursts by deinactivation of calcium T-channels, discharging at low (theta) frequency, 3) a progressive increase of the number of thalamocortical modules di...

Introduction: In this study, we intend to determine the correlation between the thickness of the cerebral cortex and the severity of the cognitive disorder in Alzheimer disease (AD). Methods: A total of 20 (14 women and 6 men) patients diagnosed with AD with a Mean age of 72.95 years, and 10 (7 women and 3 men) cognitively normal (CN) subjects with a Mean age of 70.50 years were included in th...

background and aims. there are many edentulous people with severely resorbed residual ridges and non-resilient lining mucosa that are unable to tolerate occlusal forces during functional and parafunctional movements. lining the tissue surface of dentures with a flexible material can theoretically distribute and absorb forces with cushioning effect. the aim of this study was to evaluate the effe...

BACKGROUND One contemporary view of stuttering posits that speech disfluencies arise from anomalous speech motor control. PURPOSE To verify the rest muscle tension and speech reaction time of fluent and stuttering adults. METHOD 22 adults, divided in two groups: G1--11 fluent individuals; G2--11 stutterers. Electromyography recordings (inferior orbicularis oris) were collected in two differ...

A 16-years-old female patient with painless swelling of the right side of mandible is described. She noticed the swelling from two years ago, without painful symptoms. Axial CT imaging showed buccal expansion with intact buccal and lingual cortical bone. The report of incisional biopsy was central odontogenic fibroma. Under general anesthesia the lesion was removed after ostectomy of buccal cor...

Induced pluripotent stem cell (iPSC)-derived cortical neurons potentially present a powerful new model to understand corticogenesis and neurological disease. Previous work has established that differentiation protocols can produce cortical neurons, but little has been done to characterize these at cellular resolution. In particular, it is unclear to what extent in vitro two-dimensional, relativ...

Surface-negative brain potentials indicate increased excitability of the underlying cortical neural networks. Consequently, deviant patterns of event-related potentials in schizophrenic patients reveal an atypical regulation of cortical excitability. Twelve patients with a chronic schizophrenic disorder and 12 matched control subjects were investigated using a probe paradigm: A contingent negat...