The phytopathogen Pseudomonas syringae produces the phytotoxin coronatine (COR) as a major virulence factor. COR and its precursor, coronafacic acid, function as molecular mimics of the plant signaling molecule jasmonate. A 32.8-kb plasmid-borne gene cluster mediates COR biosynthesis, which is optimal at 18 degrees C and non-detectable at 28 degrees C, the optimal growth temperature for P. syri...

The spontaneous mutant 7B-1 in tomato (Solanum lycopersicum=Lycopersicon esculentum) is a photoperiod-dependent male-sterile mutant previously reported as resistant to various abiotic stresses specifically under blue light. Since this finding improved the potential of 7B-1's use in breeding programmes, its susceptibility to stress induced by coronatine (COR), the phytotoxine produced by several...

Cordycepin (3'-deoxyadenosine), a major bioactive component isolated from Cordyceps militaris, has multiple pharmacological activities. This study is attempted to investigate whether cordycepin (COR) possesses beneficial effects on chronic unpredictable mild stress- (CUMS-) induced behavioral deficits (depression-like behaviors) and explore the possible mechanisms. ICR mice were subjected to ch...

OBJECTIVES This study sought to investigate a novel method to calculate the index of microcirculatory resistance (IMR) in the presence of significant epicardial stenosis without the need for balloon dilation to measure the coronary wedge pressure (P(w)). BACKGROUND The IMR provides a quantitative measure of coronary microvasculature status. However, in the presence of significant epicardial s...

The term “cor pulmonale” is still very popular in the medical literature, but its definition varies and there is presently no consensual definition. Forty years ago an expert committee of the World Health Organization defined cor pulmonale as “hypertrophy of the right ventricle resulting from diseases affecting the function and/or structure of the lungs . . .”. This pathological definition is i...

The oil-resin of Copaifera reticulata Ducke is used in the Brazilian folk medicine as an anti-inflammatory and healing agent. However, there are no investigations on the possible anti-inflammatory and neuroprotective roles of copaiba oil-resin (COR) after neural disorders. We have investigated the anti-inflammatory and neuroprotective effects of COR following an acute damage to the motor cortex...

ABSTRACT              Background and Objectives: Cancer and its conventional treatments may bring about some psychological and health-related symptoms leading to unstable cortisol level. Since evidence has shown that mindfulness based approaches can be helpful to reduce cortisol level, we aimed at investigating the efficacy of &n...

Silicon photodiode pyranometers have been studied extensively for application in solar energy resource assessment instruments. An example is the LI-COR, Inc. 200SZ detector that is used in rotating shadowband radiometers. While excellent results have been achieved LI-COR, Inc. calibration methods are not fully disclosed and LI-COR’s stated +/5% accuracy is less than desirable. This research aim...

cor triatriatum is an acyanotic congenital heart disease. we present a rare case of cor triatriatum sinistrum in a 6-month-old female infant who was presented with cyanosis and failure to thrive. the 2d transthoracic echocardiography and the doppler color flow imaging showed a proximal venous chamber communicating to the distal left atrium  through restrictive opening to the low-pressure, dista...

We herein describe a 34-year-old woman with a persistent left superior vena cava (PLSVC) impinging on the posterior wall of the left atrium, subdivided by a membrane at the distal part of the impingement. In this patient, a much dilated coronary sinus due to the PLSVC resulted in a membrane-like structure in the posterior wall of the left atrium with the appearance of the cor triatriatum in tra...