OBJECTIVE To compare salivary, plasma and urinary free cortisol (UFC) measurements in patients with anorexia nervosa, in whom an overdrive of the hypothalamic-pituitary-adrenal (HPA) axis is well established but information on salivary cortisol is lacking, in viscerally obese patients in whom subtle abnormalities of cortisol secretion and metabolism are postulated, and in normal-weight healthy ...

ABSTRACT Cortisol is a steroid hormone that regulates wide range of vital processes throughout the body, including metabolism and immune response. It also has very important role in helping body respond to stress. Numerous studies have been conducted around world compare development rates pigs raised indoors those outdoors, but results ambiguous and, many cases, conflicting. The objective this ...

Stress is a daily phenomenon faced by every living being and it is essential for learning. The body response to stress involves a fight and flight response in which biological changes, prepares the body for emergency action. The aim of the present study is to find out the fifteen days repeated noise, stress exposure induced alterations in the carbohydrate metabolism and its prevention by treatm...

In spite of the presence of definitive diagnostic criteria to diagnose Cushing syndrome diagnosis may become challenging. We report a young female with mild clinical features of Cushing syndrome, who had nonsuppressible oral dexamethasone suppression tests; also she had a suspicious pituitary lesion. She underwent pituitary surgery and a pituitary microadenoma (non-ACTH staining) was removed. N...

TO THE EDITOR Known steroidogenic functions of the skin that are represented by the synthesis and metabolism of androgens and estrogens (Chen et al., 2002; Zouboulis and Degitz, 2004) probably include corticosteroids (Slominski et al., 2000; Slominski, 2005). Thus, the skin expresses both the genes and proteins involved in the synthesis of adrenal corticosteroids (Slominski et al., 1996, 1999, ...

............................................................................................................................8 INTRODUCTION ...................................................................................................................9 REVIEW OF THE LITERATURE......................................................................................10 1. Drug metabolism.............

CONTEXT Extraadrenal regeneration of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 (11HSD1) is increased after a mixed meal. It is unknown which tissue is responsible and whether this reflects the complex transcriptional control of 11HSD1 or posttranscriptional control exerted by supply of reduced nicotinamide adenine dinucleotide phosphate from hexose-6-phosphate dehydrogenase. OBJE...