نتایج جستجو برای: cotton pellet
تعداد نتایج: 30284 فیلتر نتایج به سال:
is a bis-Mannich base. Mannich bases have various biological activities such as antimicrobial, cytotoxic, anticancer, analgesic, and anticonvulsant activities. It has been reported that Mannich bases such as 1-diphenylaminomethyl-3-(1-naphthylimino)-1,3-dihydroindol-3-one, 1diphenylaminomethyl-3-(4-methylphenylimino)-1,3-dihydroindol-3-one and 1,3-dicyclohexyl-5-alkyl-5-aminomethylbarbituric ac...
The cotton pellet technique was used to evaluate the effect of 5-HT and certain related compounds on granuloma formation in the rat. 5-HT (10 mg/kg) significantly decreased granuloma formation, significantly increased adrenal weight, and significantly decreased thymus weight in normal rats, and significantly decreased granuloma formation and thymus weight in sham-operated rats. On the other han...
objective(s): a box-behnken design was used for evaluation of eudragit coated diclofenac pellets. the purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. materials and methods: diclofenac was loaded onto the non-pareil beads using conventional coating pan. film coating of pellets was done at the same pan. the effect of pla...
The glucocorticoid ciclesonide is the 2'R-epimer of 2'-cyclohexyl-11beta-hydroxy-21-isobutyryloxy-16bH-dioxolo[5',4':16,17]pregna-1,4-diene-3,20-dione. The active metabolite desisobutyryl-ciclesonide (des-CIC) is derived from ciclesonide by esterase cleavage of isobutyrate at the C21 position. The relative binding affinities at the rat glucocorticoid receptor were dexamethasone, 100; ciclesonid...
The present study was aimed at evaluation of the anti-inflammatory, analgesic and antipyretic activities of petroleum ether and ethanolic extract of aerial parts of Mollugo pentaphylla Linn. In experimental standard models. The results showed that the ethanolic extract significantly reduce the edema induced by carrageenan within 1 to 3 hrs. post dosing and Cotton-pellet induced granuloma models...
The effects of methanol extract of Phyllanthus amarus on different phases of in lammation were examined. Investigations were performed using different phlogistic agents-induced paw e ema, carrageenan-induced airpouch inflammation and cotton pellet granuloma in rats. Methanol extract of Phyllanthus amarus significantly inhibited carrageenan, bradykinin, serotonin and prostaglandin E1-induced paw...
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