The 10% ethanol extract of the aerial parts of Calligonum comosum (50--400 mg/kg, i.p.) significantly reduced the increase in hind paw oedema induced by carrageenan in rats. Following sub-acute oral administration of the extract (50 and 100 mg/kg, daily for 14 days), a significant anti-inflammatory activity in the cotton pellet model was observed. Pre-treatment with the extract (100, 200 and 40...

Leaf and oleoresin fractions of both alcoholic and petroleum ether extracts of Araucaria bidwillii exhibited significant prolongation of pentobarbitones sleeping time at a dose of 300 and 100 mg/kg body weight respectively in mice. This effect is more pronounced for oleoresin than the leaf extracts. Further, the two extracts seem to possess analgesic effect comparable to aspirin by writing meth...

BACKGROUND The sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden (Tiger Milk mushroom) is used as a traditional medicine to relieve cough, asthma and chronic hepatitis. The traditional uses of the sclerotium are presumably related to its anti-inflammatory effect. The present study was carried out to evaluate the anti-inflammatory activity of the sclerotial powder of L. rhinocerotis (Cooke) R...

BACKGROUND Juglans regia leaves have been used in folk medicine to alleviate inflammatory diseases. This study investigates the antinociceptive, anti-Inflammatory and acute toxicity effects of Juglans regia L. leaves in mice. METHODS 351 Male and female albino mice were divided into negative (saline), positive (morphine or diclofenac) controls as well as test groups (n=6-8). The acute (intrap...

The purpose of the present study was to investigate the anti-inflammatory properties of ethanolic extract of the leaves of Holoptelea integrifolia Planch. (EHI). The different anti-inflammatory models were used. The EHI at dose (250 and 500mg/kg p.o) was given to observe percentage inhibition of paw oedema which were comparable with indomethacin (10mg/kg p.o) used as a reference drug. The extra...

Anti-inflammatory activ ity of the plant Mollugo pentaphylla (Ethanolic Extract) was studied by using sub acute model like cotton pellet induced granuloma technique. Sterilized raw cotton was implanted in the axilla and growing region of the rat. The ethanolic extract of the plant was adminis tered orally (at dose 200mg/kg and 400 mg/kg body weight) by inhibit ing wet weight and dry weight of t...

OBJECTIVE The present study was carried out to determine the antiinflammatory and antinociceptive activities of a methanol extract of Zingiber zerumbet rhizomes (MEZZ) using various experimental model systems. MATERIALS AND METHODS The MEZZ was prepared by macerating oven-dried (50 degrees C) powdered rhizomes (1.2 kg) of Z. zerumbet in 80% methanol in a ratio of 1:20 (w/v) for 48 h. The supe...

OBJECTIVE The present study was carried out to investigate the antinociceptive and anti-inflammatory activities of virgin coconut oil (VCO) produced by the Malaysian Agriculture Research and Development Institute (MARDI) using various in vivo models. MATERIALS AND METHODS Two types of VCOs, produced via standard drying (VCOA) and fermentation (VCOB) processes were used in this study. Both VCO...

methanolic and aqueous extracts of dendrophthoe falcata linn. leaves which belongs to the loranthaceae family, were evaluated through dpph (1, 1-diphenyl -2-picryl-hydrazyl), antilipid peroxidation and nitric oxide scavenging methods to assess the antioxidant activity. methanolic and aqueous extracts of dendrophthoe falcata leaves were also evaluated for their anti-inflammatory activity by carr...

Pistacia vera L., a member of Anacardiaceae family, has been used for sedation and analgesia in traditional medicine. In this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of P. vera leaves were investigated in mice. The antinociceptive activity was studied using hot plate and writhing tests. The effect of the extracts a...