To investigate the effects of calorie restriction (CR) on behavioral performance and expression of SIRT1 and SIRT5 in rat cerebral tissues. Beginning at 18 months of age, 60 rats were randomly divided into a CR group (n = 30) and a group that remained fed ad libitum (AL; n = 30). CR rats were restricted to a diet of 60% of their daily food consumption. After 6 months of CR, CR rats displayed a ...

Background: Lower extremity injuries are frequently observed in car-to-pedestrian accidents and due to the bumper height of most cars, knee joint is one of the most damaged body parts in car-to-pedestrian collisions.Objective: The aim of this paper is first to provide an accurate Finite Element model of the knee joint and second to investigate lower limb impact biomechanics in car-to-pede...

The role of the hippocampus in delay eyeblink conditioning (DEC) remains controversial. Here, we investigated the involvement of the hippocampus in DEC with a soft tone as the conditioned stimulus (CS) by using electrolytic lesions or muscimol inactivation of guinea pig dorsal hippocampus. Interestingly, when a soft tone was used as a CS, electrolytic lesions of the hippocampus significantly re...

BACKGROUND There are still many questions related to aseptic femoral stem loosening. Systemic and local immune responses to the implanted "foreign body" is one of the reasons for loosening. The purpose of the study was to measure metal ion concentration (Ti, Co, Cr, Mo, Ni, Al) around loosened femoral stems and compare their levels around uncemented and cemented implants. METHODS This paper r...

BACKGROUND The aim of this study was to verify the intra-individual reproducibility of natural head position (NHP) in centric relation (CR) position, to prove the inter-individual differences in the Frankfort horizontal plane and sella-nasion line compared with the true horizontal line, and to establish linear norms from A-point, B-point, Pog as well as soft tissue A-point, soft tissue B-point,...

Abstract Thin sections of three Palaeozoic bryozoans reveal fossilized soft tissues that show the position organic cuticle and internal structures such as membranous sac gut. The fossilization occurred apparently due to fast burial under anoxic conditions. a in Permian trepostome Rhombotrypella superangustata is indicative progressive polypide cycle. Ordovician Graptodictya delicata behind supe...

OBJECTIVE This study investigated the correlation between choline/creatine (Cho/Cr) ratios determined by multivoxel proton magnetic resonance spectroscopy (1H-MRS) and the distribution of cancer stem-like cells (CSLCs) in high-grade gliomas. PATIENTS AND METHODS Sixteen patients with high-grade gliomas were recruited and underwent 1H-MRS examination before surgery to identify distinct tumor r...

Background and Objectives:  The aim of this study was to survey the relationship between the level of  creatinine,cardiac troponins serum and the function of  the left ventricle in patients with  kidney insufficiency,without acute coronary syndrome. Materialsand Methods:The sample  was150 patients with nondialysis chronic kidney disease without  acute  coronary  syndrome,  hospitalized  at  I...

The bivalve mollusks Tivela mactroides and Crassostrea rhizophorae are abundant along the Venezuelan coast and are widely consumed as seafood. The globally important seagrass Thalassia testudinum is also abundant in Venezuelan. We report the concentrations of Cd, Cr, Cu, Ni, V and Zn in the soft parts of Tivela mactroides and Thalassia testudinum, and the concentrations of Cd, Cr, Cu and Ni in ...

background and objectives:  the aim of this study was to survey the relationship between the level of  creatinine,cardiac troponins serum and the function of  the left ventricle in patients with  kidney insufficiency,without acute coronary syndrome.materialsand methods:the sample  was150 patients with nondialysis chronic kidney disease without  acute  coronary  syndrome,  hospitalized  at  imam...