Dear Dr. Maureen McCormick, We have carefully read with great interest your comments and concerns about the statistical results of our study. We would like to make some remarks. If we repeat the statistical analysis of our data using an analysis of variance for repeated measures, we will obtain statistically significant results similar to our previous results, both globally or in pairs except f...

Background: Patients with chemotherapy-related neutropenia and fever are usually hospitalized and treated on empirical intravenous broad-spectrum antibiotic regimens. Early diagnosis of sepsis in children with febrile neutropenia remains difficult due to non-specific clinical and laboratory signs of infection. We aimed to analyze whether IL-6 and IL-8 could define a group of patients at low ris...

An 81yearold woman was brought to the emergency department with acute onset of shaking chills. She had no upper respiratory tract symptoms and chest, back, or abdominal pains before the arrival to the hospital. Her only regular medication was a nifedipine for hypertension. On examination, she was illappearing and had shaking chills. The blood pressure was 170/87 mmHg in the right upper extremit...

BACKGROUND Balloon bionic midwifery has been applied in clinical obstetrics in China for 10 years, although played a certain role in controlling and improving the quality of obstetrics and caesarean section rate, but some questions have not been resolved. OBJECTIVE The aim of this study was to investigate the efficacy and safety of airbag midwifery. MATERIALS AND METHODS Primiparas (2410 ca...

In a randomized trial we demonstrated that in patients with UA methotrexate is an effective drug to inhibit symptoms, structural damage, and progression towards RA. However 40-50% of UApatients remit spontaneously. Therefore adequate treatment decision-making in early-UA necessitates identification of the UA-patients that will develop RA. We developed a prediction rule using data from the Leide...

BACKGROUND This is a single institutional review of aortoiliac pseudoaneurysm of various aetiologies managed with endovascular stent graft repair. METHODS From 2009 to 2014, 16 patients had endovascular stent graft inserted for pseudoaneurysm of the thoracic aorta, abdominal aorta and iliac arteries in Hospital Kuala Lumpur. Co-morbidity, causative agents, in-hospital mortality, complications...

background: chronic low-grade systemic inflammation presented in type 2 diabetes mellitus plays a major role in disease progression as well as development of micro- and macro-vascular complications of diabetes. therefore, reducing inflammation can be beneficial in prevention of diabetes complications. objectives: to investigate the association between insulin resistance and inflammatory markers...

In this article a semantic based software system for the management and monitoring of enterprise purchase processes is described and a paradigmatic case study (the Creactive Consulting S.p.A company that have developed the system) is presented. The system enables purchaser officers to search products through a semantic based engine, and navigate a semantic based catalogue in order to electronic...

The concept of left ventricular (LV) remodeling in dogs with myxomatous mitral valve disease (MMVD) includes changes in the LV occurring in response to mitral regurgitation (MR). The general aim of this thesis was to study LV remodeling and function in dogs with different severities of naturally acquired MMVD using 1) digital signal analysis technique for murmur and heart sound assessment, 2) b...