According to the interference formulation, participants in a crowded setting will experience interference to the extent that behavioral goals conflict with environmental conditions. The importance of the behavioral goals directly affects not only the magnitude of the interference but also the mechanism by which people cope with interference. It was reasoned that important goals would induce a m...

Crowding refers to the degradation of visual acuity for target optotypes with, versus without, surrounding features. Crowding is important clinically, however the effect of target-flanker spacing on acuity for symbols and pictures, compared to letters, has not been investigated. Five adults with corrected-to-normal vision had visual acuity measured for modified single target versions of Kay Pic...

Polyethylene glycols (PEGs) are widely used to perturb the conformations of nucleic acids, including G-quadruplexes. The mechanism by which PEG alters G-quadruplex conformation is poorly understood. We describe here studies designed to determine how PEG and other co-solutes affect the conformation of the human telomeric quadruplex. Osmotic stress studies using acetonitrile and ethylene glycol s...

In crowding, the perception of a target strongly deteriorates when neighboring elements are presented. Crowding is usually assumed to have the following characteristics. (a) Crowding is determined only by nearby elements within a restricted region around the target (Bouma's law). (b) Increasing the number of flankers can only deteriorate performance. (c) Target-flanker interference is feature-s...

Molecular crowding is ubiquitous within cells and affects many biological processes including protein-protein binding, enzyme activities and gene regulation. Here we revisit some generic effects of crowding using a combination of lattice simulations and reaction-diffusion simulations with the program ReaDDy. Specifically, we implement three reactions, simple binding, a diffusion-limited reactio...

A letter in the peripheral visual field is much harder to identify in the presence of nearby letters. This is called “crowding”. In general, masking is a procedure: introducing any “mask” pattern that affects discriminability of the signal. Crowding conforms to the masking paradigm, but the crowding effect is unlike ordinary masking. Here we characterize crowding, and present diagnostic tests t...

Spatial crowding refers to impaired target identification when the target is surrounded by other stimuli in space temporal crowding refers to impaired target identification when the target is surrounded by other stimuli in time previously, when spatial and temporal crowding were measured in the fovea they were interrelated with amblyopic observers but almost absent with normal observers bonneh,...

Crowding is a fundamental bottleneck in object recognition. In crowding, an object in the periphery becomes unrecognizable when surrounded by clutter or distractor objects. Crowding depends on the positions of target and distractors, both their eccentricity and their relative spacing. In all previous studies, position has been expressed in terms of retinal position. However, in a number of situ...

In peripheral vision, object identification can be impeded when a target object is flanked by other objects. This phenomenon of crowding has been attributed to basic processes associated with image encoding by the visual system, but the neural origin of crowding is not known. Determining whether crowding depends on subjective awareness of the flankers can provide information on the neural origi...

INTRODUCTION The aim of this study is to evaluate the effects of emergency department (ED) crowding on the implementation of tasks in the early resuscitation bundle during acute care of patients with severe sepsis and septic shock, as recommended by the Surviving Sepsis Campaign guidelines. METHODS We analyzed the sepsis registry from August 2008 to March 2012 for patients presenting to an ED...