Psoriasis is an inflammatory skin disorder that is inherited as a complex trait. Genetic studies have repeatedly highlighted HLA-C as the major determinant for psoriasis susceptibility, with the Cw*0602 allele conferring significant disease risk in a wide range of populations. Despite the potential importance of HLA-C variation in psoriasis, either via an effect on peptide presentation or immun...

Lignosus rhinocerus, the tiger milk mushroom, is one of the most important medicinal mushrooms used by the indigenous people of Southeast Asia and China. It has been used to treat breast cancer. A cold water extract (LR-CW) prepared from the sclerotia of L. rhinocerus cultivar was found to exhibit antiproliferative activity against human breast carcinoma (MCF-7) and human lung carcinoma (A549),...

In this paper we are interested in finite connected 2-dimensional CTF-complexes, each with a single 2-celL We show any two such complexes have the same homotopy type if their fundamental groups are isomorphic. In fact, there is a homotopy equivalence inducing any isomorphism of the fundamental groups. We also study the homotopy factorizations of such spaces into finite sums. In this paper we ar...

Psoriasis is an immune-mediated skin disorder that is inherited as a complex genetic trait. Although genome-wide association scans (GWAS) have identified 36 disease susceptibility regions, more than 50% of the genetic variance can be attributed to a single Major Histocompatibility Complex (MHC) locus, known as PSORS1. Genetic studies indicate that HLA-C is the strongest PSORS1 candidate gene, s...

This study investigated the psychoanalytic hypothesis that intensity of the female castration complex (FCC) is greater in women with a masculine social role than in those with a feminine social role. Ss were normal, collegeeducated women, ages 30-55, divided into 2 groups: 26 career women (CW), unmarried, and in masculine occupations; and 25 homemakers, married, with 2 or more children, and not...

Abstract Funding Acknowledgements Type of funding sources: None. Background COVID-19 outbreak nudged worldwide health systems to reallocate resources from other areas help fighting against this novel infectious disease. Consequently, accuracy and quality care cardiovascular patients was partially compromised. Moreover, fear get hospital made stay home despite the presence symptoms that would ha...

The paper is devoted to the homotopy classification of C*-algebras of continuous functions on a finite CW-complex with values in a UHF-algebra. The relevant invariants are based on (connective) K-theory.

Infection by necrotrophs is a complex process that starts with the breakdown of the cell wall (CW) matrix initiated by CW-degrading enzymes and results in an extensive tissue maceration. Plants exploit induced defense mechanisms based on biochemical modification of the CW components to protect themselves from enzymatic degradation. The pectin matrix is the main CW target of Botrytis cinerea, an...

Plant cell wall (CW) polysaccharides are responsible for the mechanical strength and growth of plant cells; however, the high-resolution structure and dynamics of the CW polysaccharides are still poorly understood because of the insoluble nature of these molecules. Here, we use 2D and 3D magic-angle-spinning (MAS) solid-state NMR (SSNMR) to investigate the structural role of pectins in the plan...