نتایج جستجو برای: cytotoxicity effect

تعداد نتایج: 1675895  

Journal: :iranian journal of basic medical sciences 0
leila hosseinzadeh medical toxicology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran javad behravan biotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran fatemeh mosaffa biotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran gholamreza bahrami medical biology research center, kermanshah university of medical sciences, kermanshah, iran ahmad reza bahrami faculty of sciences, ferdowsi university of mashhad, mashhad, iran gholamreza karimi medical toxicology research centre, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s) doxorubicin (dox), a widely used chemotherapeutic agent can give rise to serve cardiotoxicity by inducing apoptosis. curcumin, the active compound of the rhizome of curcuma longa l. has anti-inflammatory, antioxidant and anti-proliferative activities. curcumin has been identified to increase cytotoxicity in several cancer cell lines in combination with dox, but there is no study ab...

Journal: :jundishapur journal of natural pharmaceutical products 0
elina asiaei shiraz university of medical sciences, international branch, shiraz, iran melika farshad faculty of dentistry, shiraz university of medical sciences, shiraz, iran mohammad abdollahi toxicology and diseases group, pharmaceutical sciences research center, tehran university of medical sciences, tehran 1417614411, iran akram jamshidzadeh pharmaceutical sciences research center, shiraz university of medical sciences, shiraz, iran; department of pharmacology and toxicology, pharmaceutical sciences research center, shiraz university of medical sciences, shiraz, iran. tel: +98-7132424126, fax: +98-7132426070 amin reza akbarizadeh pharmaceutical sciences research center, shiraz university of medical sciences, shiraz, iran mohammad amin soltanzadeh shiraz university of medical sciences, international branch, shiraz, iran

in the present study, free-radical-scavenging and antioxidant activities of angipars™, an herbal extract which has been registered as a therapeutic drug for diabetic foot ulcer, were examined. we investigated the protective effect of angipars™ on cytotoxicity produced by exposure to h2o2 (300 µm) in hepg2 and a549 cell lines, using mtt assay, glutathione (gsh) content analysis, and lipid peroxi...

Journal: :journal of reports in pharmaceutical sciences 0
hanifeh nazari tarhan leila hosseinzadeh alireza aliabadi babak gholamine alireza foroumadi

apoptosis, or programmed cell death, is an essential physiological process that plays a critical role in development and tissue homeostasis. caspases, a family of cysteine-dependent aspartate-directed proteases, play a critical role in the initiation and execution of apoptosis. in this study, cytotoxicity and apoptogenic effect of 2-phenyl 4-carboxamide derivatives were evaluated in sknmc (huma...

Objective(s): In this work, CuO- NiO nano-composites were synthesized via free-surfactant co-precipitation method and then their physiochemical properties, as well as cytotoxicity and antifungal effects, were studied. Methods: The structural and optical properties of CuO-NiO nanostructures were analyzed by X-ray diffraction (XRD), scanning electron micros...

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