نتایج جستجو برای: dar el maarefal

تعداد نتایج: 289591  

Journal: :The Journal of biological chemistry 2004
Yoon Namkung David R Sibley

Previously, D2 dopamine receptors (D2 DARs) have been shown to undergo G-protein-coupled receptor kinase phosphorylation in an agonist-specific fashion. We have now investigated the ability of the second messenger-activated protein kinases, protein kinase A (PKA) and protein kinase C (PKC), to mediate phosphorylation and desensitization of the D2 DAR. HEK293T cells were transiently transfected ...

2015
Meredith L Montgomery Stanley E Kim Jonathan Dyce Antonio Pozzi

BACKGROUND Loss of dorsal acetabular rim (DAR) is a common sequela to canine hip dysplasia. The purpose of this study is to evaluate the effect of DAR loss on the initial stability of the cementless (BFX) acetabular cup. BFX cups were implanted into foam blocks reamed to resemble acetabulae with simulated 0, 25, 50, and 75% DAR loss. Models were tested in edge loading of the lateral surface of ...

Journal: :Spine 2016
Xiao-Bin Wang Lawrence G Lenke Earl Thuet Kathy Blanke Linda A Koester Michael Roth

STUDY DESIGN Retrospective review of prospectively collected data. OBJECTIVE To assess the value of the deformity angular ratio (DAR, maximum Cobb measurement divided by number of vertebrae involved) in evaluating the severity of spinal deformity, and predicting the risk of neurologic deficit in posterior vertebral column resection (PVCR). SUMMARY OF BACKGROUND DATA Although the literature ...

Journal: :Journal of virology 1974
M F Mullarkey J F Hruska K K Takemoto

The proteins of simian virus 40 (SV40) and two human papovaviruses, the hemagglutinating BK virus and the non-hemagglutinating DAR virus, were analyzed and compared by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The virions of SV40 and DAR contain seven proteins. By molecular weight analysis the constituent proteins of SV40 and DAR are identical. Approximately 84% of the viral pr...

Journal: :Journal of traumatic stress 2004
David Forbes Graeme Hawthorne Peter Elliott Tony McHugh Dirk Biddle Mark Creamer Raymond W Novaco

There is a need for a brief specific measure of anger for use in assessment of posttraumatic mental health problems. One unpublished short scale is the Dimensions of Anger Reactions (DAR; R. Novaco, 1975). This study examined the psychometric properties of the DAR using intake and 12-month data for 192 Australian Vietnam veterans with combat-related PTSD. Results showed the DAR to be unidimensi...

2014
Jingbo Xiao R. Benjamin Free Elena Barnaeva Jennie L. Conroy Trevor Doyle Brittney Miller Marthe Bryant-Genevier Mercedes K. Taylor Xin Hu Andrés E. Dulcey Noel Southall Marc Ferrer Steve Titus Wei Zheng David R. Sibley Juan J. Marugan

The D2 dopamine receptor (D2 DAR) is one of the most validated drug targets for neuropsychiatric and endocrine disorders. However, clinically approved drugs targeting D2 DAR display poor selectivity between the D2 and other receptors, especially the D3 DAR. This lack of selectivity may lead to undesirable side effects. Here we describe the chemical and pharmacological characterization of a nove...

2009
Laura Rupp

Dialect speakers in the North of England use vowel-less forms of the definite article (the) which are unattested in English varieties elsewhere and have been termed Definite Article Reduction (DAR). Previous research on DAR has provided detailed phonological descriptions, but less insight has been gained into other aspects of DAR like its emergence and the northern pattern of occurrence. I demo...

Journal: :Journal of bacteriology 1982
A C Skjold D H Ezekiel

Studies involving lambda phage transduction of the D-arabinose utilization gene (dar+) in Escherichia coli K-12 indicated the product of this gene to be a transdominant activator. An apparent anomaly regarding this hypothesis exists in that a diploid recessive lysogen (lambda dar-/dar-) can spontaneously become capable of growth on D-arabinose.

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