I review the tunneling, Hartle-Hawking and Linde proposals for the wave function of the universe and comment on the recent work on quantum creation of open universes.

.......This issue of IEEE Micro is a little bit different, to say the least. It includes four debates from the Computer Architecture Research Directions (CARD) workshop that was held as part of the 13th Annual IEEE/ACM International Symposium on High-Performance Computer Architecture in February 2007. The organizers approached me about a special Micro issue about CARD and I said, ‘‘Why not?’’ W...

debate over whether economic sanctions "work" is mired in a scholarly limbo. One writer contends that recent international relations scholarship has promoted optimism about the utility of such measures and sets out to challenge this trend} while another notes the pessimism that "pervades the sanctions literature" and proceeds to argue that it is unjustified.2 A third scholar cites the sanctions...

This toxicology update reviews research over the past four years since publication in 2004 of the 1⁄4rst measurement of intact esters of p-hydroxybenzoic acid (parabens) in human breast cancer tissues, and the suggestion that their presence in the human body might originate from topical application of bodycare cosmetics. The presence of intact paraben esters in human body tissues has now been c...

and the most frequent genetic aetiology of severe testiculopathy. Carlo Foresta1, Enrico Moro and Alberto Ferlin Basic research in the field of the genetics of male infertility University of Padova, Department of Medical and Surgical has been of primary importance to drive the current clinical Sciences, Clinica Medica 3, Via Ospedale 105, 35128 Padova, Italy approach of the infertile patient, a...

REPORTS Recombinant DNA: Examples ofPresent-Day Research:J.Abelson. Charon Phages: Safer Derivatives ofBacteriophage Lambda forDNA Cloning: F. R. Blattner et al. . Recombinational Switch for Gene Expression: J. Zieg et al. Gene Cloning and Containment Properties of Plasmid Col El and Its Derivatives: K. A. Armstrong, V. Hershfield, D. R. Helinski. EK2 Derivatives ofBacteriophage Lambda Useful i...

Copyright © 2008 American Heart Association. All rights reserved. Print ISSN: 0194-911X. Online 72514 Hypertension is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX DOI: 10.1161/HYPERTENSIONAHA.107.105742 2008;51;952-959; originally published online Feb 7, 2008; Hypertension Megan Coylewright, Jane F. Reckelhoff and Pamela Ouyang Menopause and Hypertension: An A...

Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate. The Mount Sinai School of Medicine is accredited by t...

thelium: increased monolayer permeability and induction of procoagulant properties. J Clin Invest 1990; 85:1090–1098 4 Yan SF, Ogawa S, Stern DM, et al. Hypoxia-induced modulation of endothelial cell properties: regulation of barrierfunction and expression of interleukin-6. Kidney Int 1997; 51:419–425 5 Putinati S, Ballerin L, Piattella M, et al. Is it possible to predict the success of non-inv...