BACKGROUND PUVA photochemotherapy is indicated to treat mycosis fungoides, either as monotherapy in the earlier stages of the disease or in combination with other drugs in more advanced stages of evolution. OBJECTIVES – To evaluate PUVA photochemotherapy response in patients with mycosis fungoides. METHODS From January 1996 to November 2003, 17 patients with a diagnosis of mycosis fungoides wer...

Abnormal hair development and regeneration occurs in some skin diseases, including lymphomas when hair follicles are eliminated. Otherwise, neoplastic cells, both malignant and benign, local occurring and metastatic, can cause alopecia of the scalp. In lymphomas alopecia can develop due to direct infiltration by the disease, or it may be a secondary or paraneoplastic manifestation. Total -body ...

Bullous mycosis fungoides is a rare entity of cutaneous T-cell lymphomas; however, it can be particularly aggressive with an unfavorable prognosis. Mechanism of formation of bullous lesions in bullous lymphoma remains poorly understood, it can be explained by excessive epidermotropism or tumor infiltration’s toxicity. We report the case of a bullous erythrodermic mycosis fungoides.

Pagetoid reticulosis is a rare variant of mycosis fungoides that presents with a large, usually single, erythematous, slowly growing scaly plaque containing an intraepidermal proliferation of neoplastic T lymphocytes. Histopathologically, this disease has distinctive attributes. In this report, we present two cases of pagetoid reticulosis, compare its microscopic features to those of 'classical...

Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, is histologically characterized by atypical T lymphocytes with cerebriform nuclei that infiltrate the epidermis. Alope

ALCL: anaplastic large cell lymphoma CL: composite lymphoma EBV: Epstein-Barr virus MF: mycosis fungoides INTRODUCTION Patients with mycosis fungoides (MF) are at increased risk of a second malignant neoplasm, especially lymphoma. We report a sexagenarian with a 14-year history of patch MF, stage IB, who had intravascular cutaneous anaplastic large cell lymphoma (ALCL) and cutaneous composite l...

A patient with mycosis fungoides developed a nephrotic syndrome. Renal biopsy revealed deposits of a highly organized fibrillar material which did not stain with the typical amyloid stains; this picture was consistent with the diagnosis of non-amyloidotic fibrillary glomerulopathy or immunotactoid glomerulopathy. We believe this is the first case reported of immunotactoid glomerulopathy associa...