hyperpigmentation over face in a neonate is rare and the differentials for the same are also rare. congenital chickengunya, fungal and viral infections, drug rash are few differentials. chikungunya virus (chikv) infection manifesting in neonates is very rare. the prevalence of the entity was described only recently. we describe a neonate with hyperpigmentation on day 3 of life with stormy cours...

Background & aim: Sepsis is a major cause of neonatal mortality in the developing countries. The prevention and management of this infection require informed workforce and availability of necessary resources and equipment. Regarding this, the present study was conducted to investigate healthcare workers’ neonatal sepsis knowledge; prevention and management strategies in use for the control of t...

Background: Sepsis or blood stream infection is a clinical lethal syndrome with severe systemic inflammatory response to infection, if not treated quickly, is associated with dangerous consequences and high morbidity and mortality. The traditional and conventional method for identification of sepsis is blood culture method which is so time-consuming and long that it eliminates the possibility o...

Patients with immune thrombocytopenia (ITP) who relapse after an initial trial of corticosteroid treatment present a therapeutic challenge. Current guidelines recommend consideration of splenectomy, despite the known risks associated with surgery and the postsplenectomy state. To better define these risks, we identified a cohort of 9976 patients with ITP, 1762 of whom underwent splenectomy. The...

OBJECTIVE To assess whether the Belgian Hospital Discharge Dataset (B-HDDS) is a valid source for the detection of adverse events in acute hospitals. DESIGN, SETTING AND PARTICIPANTS Retrospective review of 1515 patient records in eight acute Belgian hospitals for the year 2005. MAIN OUTCOME MEASURES Predictive value of the B-HDDS and medical record reviews and degree of correspondence betw...

Sepsis is a devastating disease process characterized by a systemic inflammatory response in the host, evoked by a known or suspected pathogen. Staphylococcus aureus has emerged as a leading etiologic agent of sepsis, owing to its propensity to cause deep-seated tissue infection and bacteremia [1]. S. aureus harbors an arsenal of virulence factors to facilitate tissue adhesion, immune evasion, ...

BACKGROUND Critically ill patients may develop muscle weakness or paralysis during the course of sepsis and multiple-organ failure. We studied peripheral nerve and muscle disorders (NMD) in comatose patients. METHOD Comatose patients who developed paralysis associated with absent deep-tendon reflexes had electroneuromyography (ENMG) and muscle-nerve biopsy specimens taken. Onset and duration ...

Background: Neonatal sepsis is a major cause of mortality and morbidity, especially in developing countries. The goal of the present study was to determine the bacterial etiology and antibiotic sensitivity patterns of neonatal sepsis. Methods: This cross sectional study was conducted on 208 neonates admitted with clinically suspected sepsis over a period of 30 months. Sepsis was divided into ea...

Background Neonatal sepsis is one of the most critical illness in neonates that is responsible for a great proportion of morbidity and mortality in neonates so early diagnosis and identification of high risk cases is a challenging aim of our study. The purpose of this study was to investigate the prognostic value of red cell distribution width (RDW), in neonatal sepsis at the time of admission ...