OBJECTIVE As a main cellular component within the disc, nucleus pulposus (NP) cells play important roles in disc physiology. However, little is known on the biologic hallmarks of human NP cells. Therefore, the present study aimed to address the features of human NP cells. METHODS Human NP samples were collected from normal cadavers, patients with scoliosis and disc degeneration as normal, dis...

A radiographic study on Knee-Spine Syndrome in the coronal plane a, Harato, K; Otani, T; Yoshida, H. a Department of Orthopedic Surgery, IUHW Mita Hospital, Tokyo, Japan, b Department of Sports Clinic, Keio University, Tokyo, Japan c Department of Orthopedic Surgery, NHO Tochigi Hospital, Utsunomiya, Japan, [email protected] Introduction Clinically, back pain is present in 54.6 % of patients...

We reviewed the records and physical findings of twenty-three young adults who had had significant untreated limb-length inequality, present since childhood. The spine was studied radiographically and clinically before and after neutralization of the discrepancy of limb lengths with a lift. Movements of the spine also were measured. A significant asymmetry of lateral flexion of the spine remain...

BACKGROUND Degenerative adult de novo (DAD) scoliosis appears characteristically in the sixth or seventh decade with symptoms of severe back pain and radiculopathy or spinal claudication. The aim of this study was to enhance the knowledge of perioperative complications and detect possible risk factors in this selective DAD scoliosis surgery. METHODS This retrospective study included only pati...

OBJECTIVE The objectives of this study were to clarify the short-term effects of transforaminal epidural steroid injection (TFESI) for degenerative lumbar scoliosis combined with spinal stenosis (DLSS), and to extrapolate factors relating to the prognosis of treatment. METHOD Thirty-six patients with lumbar radicular pain from DLSS were enrolled. Subjects were randomly assigned to one of two ...

Introduction The potential of scoliosis progressing into a clinically significant spinal deformity drives the detection, diagnosis, and treatment decisions for skeletally immature children. In these cases, growth is the potential enemy. In the early stages, the primary concerns may be mainly abnormal physical appearance and diminished self esteem. In more advanced cases, the overriding issues m...

BACKGROUND The aim of this study was to analyze the true outcomes of a unique cohort of patients with spinal deformities who were treated as children and followed for 40 or more years. METHODS Altogether, 23 patients were reviewed who had been originally treated in our community, whose original charts and radiographs were still available, and who had undergone recent evaluation. RESULTS The...

The clinical efficacy of reduction and fusion surgery and the suitable range of fusion-segment were evaluated in 12 pediatric patients treated for high-grade spondylolisthesis. Pre/post-operative clinical and radiological assessments were analyzed. A transient L5 nerve root paralysis was observed in one patient with L5 spondylolisthesis. No degenerative spondylolisthesis or adjacent segmental i...