Periodontitis is a major cause for tooth loss, which affects about 15% of the adult population. Cementum regeneration has been the crux of constructing the periodontal complex. Cementum protein 1 (CEMP1) is a cementum-specific protein that can induce cementogenic differentiation. In this study, poly(ethylene glycol) (PEG)-stabilized amorphous calcium phosphate (ACP) nanoparticles were prepared ...

Little is known about the molecular mechanisms that regulate the cementogenesis process, because specific cementum markers are not yet available. To investigate whether a cementoblastoma-conditioned medium-derived protein (CP) could be useful as a cementum biological marker, we studied its expression and distribution in human periodontal tissues, human periodontal ligament, alveolar bone, and c...

. AIM: This study evaluates marginal sealing ability of currently available three self-etching adhesives in class V micro fill composite restorations. Materials and methods: Forty five human central incisors, divided in to three groups and class V cavities were prepared on the facial surface of teeth with occlusal margin in enamel and gingival margin in dentin/cementum. The cavities were restor...

Plate I Photomicrographs of the human tooth germ. a. At the cap stage of development. The black punctate material is glycogen. b. At the bell stage of development. c. Undecalcified section illustrating the marked Schiff positivity of the odontoblast cytoplasm during dentinogenesis. d. Undecalcified section illustrating the distribution of alkaline phosphatase. Note the intense enzyme activity i...

Artificial cemented sand test samples were prepared by using ordinary Portland cement (OPC) as the cementing agent. Through uniaxial compression tests and consolidated drained triaxial compression tests, the stress-strain curves of the artificial cemented sand with different cementing agent contents (0.01, 0.03, 0.05 and 0.08) under various confining pressures (0.00 MPa, 0.25 MPa, 0.50 MPa and ...

To overcome the disadvantages of computer-aided design/computer-aided manufacturing (CAD/CAM) processed indirect restorations using glass-ceramics and other ceramics, resin nano ceramic, which has high strength and wear resistance with improved polish retention and optical properties, was introduced. The purpose of this study was to evaluate the shear bond strength and fracture pattern of indir...

Subjects The study sample was composed 152 children from 5 primary schools in the Ilala District (one of the districts of the capital city Dar es Salaam, Tanzania) and the mean age at baseline was 11 years. These children were in need of 2 or more restorations on permanent molars. A total of 430 matched contralateral restorations were randomly placed in 152 children, and at the 6-year follow-up...

PURPOSE To evaluate the fixation strength at the interface between the Kerboull-type plate and bone cement in 6 experimental conditions. METHODS Experimental materials comprised a simulated acetabular block, a simulated Kerboulltype plate, a pressuriser cover, a pressuriser arm, and bone cement. The simulated Kerboull-type plate was placed on the simulated acetabular block, with the pressuris...

Periodontal regeneration has been challenged with chemical reagents and/or biological approaches, however, there is still no sufficient technique that can regenerate complete periodontium, including alveolar bone, cementum, and well-oriented collagen fibers. The purpose of this study was to examine multi-layered sheets of periodontal ligament (PDL)-derived cells for periodontal regeneration. Ca...