Since new drinking water regulations were implemented in England and Wales in 2000, cryptosporidiosis has been significantly reduced in the first half of the year but not in the second. We estimate an annual reduction in disease of 905 reported cases and approximately 6,700 total cases.

This longitudinal study examined the effect of the birth of the 1st child on relationship functioning using data from 218 couples (436 individuals) over the course of the first 8 years of marriage. Compared with prebirth levels and trajectories, parents showed sudden deterioration following birth on observed and self-reported measures of positive and negative aspects of relationship functioning...

Asexual species accumulate deleterious mutations through an irreversible process known as Muller's ratchet. Attempts to quantify the rate of the ratchet have ignored the role of temporal environmental heterogeneity even though it is common in nature and has the potential to affect overall ratchet rate. Here we examine Muller's ratchet in the context of conditional neutrality (i.e., mutations th...

Leli and Filskov (1979) reported cross-validated classification accuracy that equalled 83% for a discriminant function derived on two measures of intellectual deterioration. This investigation made a preliminary assessment of the clinical utility of this function through a clinical-actuarial classification paradigm. Wechsler-Bellevue Intelligence Scale Form I protocols from 12 nonpsychotic noni...

HEALTH ISSUE: Total fertility rates (TFRs) have decreased worldwide. The Canadian fertility rate has gone from 3.90 per woman in 1960 to 1.49 in 2000. However, not many studies have examined the impact on women's health of reduced fertility rates, delayed fertility and more births to unmarried women. This paper presents information on the relation between family size and specific determinants o...

Ageing in many organisms, including humans, is accompanied by marked alterations in both general and specific protein synthesis. Protein synthesis is normally under tight control by a broad array of regulatory factors, which facilitate appropriate rates of mRNA translation. Are the wide changes in protein synthesis simply a corollary of the ageing process or do they have a causative role in sen...

an important problem in performance evaluations of irrigation systems is the difficulty of the determining share of structural and operational elements and determining improvement solutions. in most studies, the combined impact of structural and operational elements on the performance of irrigation systems is assessed. some researchers try to separate the effects of structural and operational e...

this paper presents an inventory model for deteriorating items in which shortages are allowed. it is assumed that the production rate is proportional to the demand rate and greater than demand rate. the inventory model is developed by considering four different circumstances. the optimal of the problem is obtained with the help of mathematica 7 software. numerical examples are given to illustra...

INTRODUCTION Nurses often recognize deterioration in patients through intuition rather than through routine measurement of vital signs. Adding the 'worry or concern' sign to the Rapid Response System provides opportunities for nurses to act upon their intuitive feelings. Identifying what triggers nurses to be worried or concerned might help to put intuition into words, and potentially empower n...

OBJECTIVES To analyse how economic downturns affect child mortality both globally and among subgroups of countries of variable income levels. DESIGN Retrospective observational study using economic data from the World Bank's Development Indicators and Global Development Finance (2013 edition). Child mortality data were sourced from the Institute for Health Metrics and Evaluation. SETTING Gl...