It has been recently shown that in rat liver there are two enzymes which phosphorylate glucose to glucose 6-phosphate. One of them is a hexokinase with a great affinity for glucose and, like those of other animal tissues it is inhibited by glucose 6phosphate; the other one, named glucokinase, has a low affinity for glucose, is not inhibited by glucose 6phosphate, and appears to be responsible f...

Aims To examine the relationship between visual acuity in each eye and Quality of Life (QoL) outcomes in people with diabetic macular oedema. Methods Cross sectional retrospective analysis of data collected at baseline in 289 people entered into a randomized clinical trial with diabetic macular oedema which investigated the safety and efficacy of a vascular endothelial growth factor inhibitor, ...

Aims To assess barriers and facilitators of participation in a supervised exercise programme, and adherence to exercise after programme completion. Methods Focusgroupdiscussionsaddressed factorswhichcould facilitate attendance, current engagement in exercise, reasons for continuing or discontinuing regular exercise and ways to integrate exercise into daily life. Three focus groups, with a total...

Aim To analyse the cost-effectiveness of different interventions for Type 2 diabetes prevention within a common framework. Methods A micro-simulation model was developed to evaluate the cost-effectiveness of a range of diabetes prevention interventions including: (1) soft drinks taxation; (2) retail policy in socially deprived areas; (3) workplace intervention; (4) community-based intervention;...

background: diabetes is a multi factor disease of metabolic disorders, increasing of blood glucose or hyperglycemia. it can cause by secretion abnormality, insulin function or both. sweet diabetic is most common disease and about 150* 1 05 people are suffered from its thought the world. it is predicted that it will reach up to 300*l06 till 2045 . methods: a descriptive study using logical order...

vitamin d and diabetes mellitus

conclusions the lh is a common problem in insulin-treated jordanian patients with t2dm. more efforts are needed to educate patients and health workers on simple interventions such as using shorter needles and frequent rotation of the insulin injection sites to avoid lh and improve glycemic control. results the overall prevalence of lh was 37.3% (27.4% grade 1, 9.7% grade 2, and 0.2% grade 3). t...

background : pancreas as the insulin-producing gland is subjected to destruction and change in the diabetes-producing process. realtime sonography can assess the gland in 95% of cases and its accuracy in diagnosis of pancreatic disease matches that of ct-scan. the purpose of this study was to evaluate pancreatic diameter and echogenicity by sonography and to examine the correlation of these two...