Background. The COVID-19 pandemic has an impact on the incidence of type 1 diabetes and frequency diabetic ketoacidosis. However, exact relationships are unclear. It is also not known whether this a short-term phenomenon or effects have long-term relevance. Furthermore, it these changes during due to direct SARS-CoV-2 in patient’s environment pandemic. Methods. We conducted extensive literature...

Ketoacidotic coma remains an important cause of mortality in children and adolescents with diabetes mellitus. Despite this, it is preventable by educating patients and their attendants, except at first onset of the disease. The management of ketoacidotic coma is important not only in patients with type 1 diabetes, but also with type 2 diabetes(so-called ‘soft drink ketosis’). This review discus...

The incidence of functional intussusception is extremely rare in adults. A 23-year-old woman, previously diagnosed with type 1 diabetes mellitus (DM), complained of colicky abdominal pain associated with vomiting of 1-day duration. Currant jelly stool was observed. Irrespective of hydration and intravenous insulin injection under the diagnosis of diabetic ketoacidosis (DKA), her abdominal pain ...

Background: Type 1 diabetes mellitus (T1DM) results from the destruction of pancreatic beta cells, genetic and environmental factors are believed to be major component for the development of disease. Viruses have been suspected to contribute to the onset of T1DM. Case report: We describe here a patient who had diabetic ketoacidosis with acute fulminant hepatitis following asymptomatic infection...

Result: A 43-year-old man with a history of diabetes mellitus presented with vomiting, diarrhea and fatigue for 2 days and his laboratory tests showed high serum glucose and diabetic ketoacidosis. CT scan of the abdomen showed no abnormity. Intravenous fluid resuscitation and continuous insulin infusion was initiated. Omeprazole was started for possible upper gastrointestinal hemorrhage. Hypoca...

INCIDENCE — Clinically significant cerebral edema occurs in approximately 1 percent of episodes of diabetic ketoacidosis in children and has a mortality rate of 20 to 90 percent; 50 to 80 percent of diabetes-related deaths are caused by cerebral edema [1-3]. Overall mortality rates for diabetic ketoacidosis (DKA) in children range from 0.15 to 0.51 percent in national population studies in Cana...

Data from the UK National Diabetes audit shows a crude one year incidence of 3.6% among people with type 1 diabetes. In the UK nearly 4% of people with type 1 diabetes experience DKA each year, the number of DKA episodes per 100 patient years is 4.8, about 6% of cases of DKA occur in adults newly presenting with type 1 diabetes, and about 8% of episodes occur in hospital patients who did not pr...

A diagnosis of diabetic ketoacidosis requires the patient's plasma glucose concentration to be above 250 mg per dL (although it usually is much higher), the pH level to be less than 7.30, and the bicarbonate level to be 18 mEq per L or less. Beta-hydroxybutyrate is a better measurement of the degree of ketosis than serum ketones. Intravenous insulin and fluid replacement are the mainstays of th...

Hypoglycemia in diabetic patients is usually caused by excessive exogenous insulin or the administration of an insulin secretagogue relative to the prevailing glucose concentration. Thus, the clinical manifestations of hypoglycemia are usually not observed in diabetic patients after either insulin or an oral hypoglycemic agent is discontinued. In contrast, diabetic ketoacidosis results from rel...

DKA is a state of decompensation metabolic chaos characterized by triassic hyperglycemia, acidosis, and ketosis which one the most serious life-threatening acute complications diabetes mellitus. Diabetic Ketoacidosis (DKA) requires proper treatment immediate treatment. Management insulin therapy, intravenous administration fluids key component management to expand intravascular, interstitial, i...