INTRODUCTION This is the fi rst prospective study done locally to determine the effectiveness of vacuum-assisted closure (VAC) therapy in the healing of chronic diabetic foot ulcers. MATERIALS AND METHODS An electronic vacuum pump was used to apply controlled negative pressure evenly across the wound surface. Changes in wound dimension, presence of wound granulation and infection status of di...

We examined the determinants of microbial load in infected diabetic foot ulcers in 62 patients (38 men and 24 women, mean age: 65.63 ± 12.71 years) with clinically infected diabetic foot ulcers. Tissue cultures were taken from ulcers by 4 mm punches. Ulcer grade (University of Texas classification), neuropathy disability score (NDS), neuropathy symptom score (NSS), ankle-brachial index (ABI), p...

BACKGROUND Diabetic foot infections are a common and serious problem, yet few randomised trials of adequate quality have compared the efficacy of the various antibiotic regimens available for their treatment. Our aim was to assess the efficacy and safety of ertapenem versus piperacillin/tazobactam for foot infections. METHODS We did a randomised, double-blinded, multicentre trial in adults (n...

Aims/Objectives People with diabetes are at a significantly increased risk of foot ulceration, infection, and lower extremity amputation. The Scottish Intercollegiate Guidelines Network1 (SIGN) published guidelines on the care and management of foot complications in patients with diabetes in 2010. Little data is available on the extent to which these guidelines have been implemented, or on the ...

Diabetic foot ulcer classification systems use the presence of wound infection (bacteria present within wound) and ischaemia (restricted blood supply) as vital clinical indicators for treatment prediction healing. Studies investigating automated computerised methods classifying diabetic wounds are limited due to a paucity publicly available datasets severe data imbalance in those few that exist...

we report a catalase-negative staphylococcus aureus isolated from a 56-year-old male diabetic patient with foot ulcer who attended our surgery ward. species identification was confirmed by gram staining, standard biochemical tests and pcr amplification of the nuc and fem genes. antibiotic susceptibility showed that the strain was sensitive to imepenem, chloramphenicol, amoxicillin, vancomycin a...

OBJECTIVE The purpose of this study was to evaluate risk factors for methicillin-resistant Staphylococcus aureus (MRSA) in patients hospitalized for diabetic foot infections. METHODS We reviewed hospital admissions for foot infections in patients with diabetes which had nasal swabs, and anaerobic and aerobic tissue cultures at the time of admission. Data collected included patient characteris...

Diabetic foot ulcers and infections are common complications of diabetic disease. Additionally, these a cause morbidity impose substantial burden to the patient society. It is imperative understand major contributing factors, namely, neuropathy, peripheral arterial disease, immune system dysfunction in order guide treatment. Management disease begins with detailed history thorough physical exam...

Discovery of osteitis may be delayed because of late appearance of X-ray signs in patients with diabetic foot. Scintigraphy with labelled leukocytes is able to detect flogosis but often misses bone involvement, due to inadequate resolution of Anger camera, the commonest detector used in nuclear medicine. Radioguided surgery and biopsy with high resolution scintigraphy (HRS) started to be studie...

Yokenella regensburgei, a member of the family Enterobacteriaceae, is rarely isolated in humans. Here, we report a 71-year-old man with diabetic foot infection from which Y. regensburgei was isolated. Following debridement and disarticulation of the foot, an exudate specimen was obtained, from which Gramnegative bacilli were recovered. The organism was identified as Y. regensburgei using the Vi...