BACKGROUND Infants born to diabetic women have certain distinctive characteristics, including large size and high morbidity risks. The neonatal mortality rate is over five times that of infants of non diabetic mothers and is higher at all gestational ages and birth weight for gestational age (GA) categories.The study aimed to determine morbidity and mortality pattern amongst infants of diabetic...

centa was higher in Finnish than in Danish samples (Shen et al. 2007). Country of origin was therefore included as a covariate in a binary logistic regression. We found no significant difference between mothers with and without diabetes for fat content in breast milk or placenta (p = 0.975 and 0.107, respectively) or the sum of the most prevalent BDE congeners (p = 0.233 and 0.317, respectively...

Macrosomia or fetal obesity is a frequent complication of pregnancy in diabetes mellitus. Several alterations observed in carbohydrate and lipid metabolism in macrosomic infants of diabetic mothers are thought to be a consequence of maternal hyperglycaemia leading to fetal hyperinsulinaemia. Macrosomic infants of diabetic mothers are prone to the development of glucose intolerance, obesity and ...

Kemball, M. L., McIver, C., Milner, R. D. G., Nourse, C. H., Schiff, D., Tiernan, J. R. (1970). Archives of Disease in Childhood, 45, 696. Neonatal hypoglycaemia in infants of diabetic mothers given sulphonylurea drugs in pregnancy. Three infants whose diabetic mothers were given chlorpropamide and one infant whose diabetic mother was given acetohexamide up to the time of delivery were studied ...

OBJECTIVE By age 5 years, offspring of diabetic mothers (ODMs) are heavier and have altered glucose metabolism compared with offspring of mothers without diabetes (non-DMs). This study evaluates the growth pattern of ODMs before the age of 5 years. RESEARCH DESIGN AND METHODS Anthropometric measures (z scores) from birth, 1.5 years, and 7.7 years in Pima Indian children were compared by mater...

Objective: To find out the prevalence of macrosomic births and its obstetric outcome in diabetic and non diabetic maternities of Saudi nationality of Al-Jouf Region. Material and Methods: This one year study was carried out from January 2012 to December 2012 in Department of Obstetrics and Gynaecology at “Al-Jouf Maternity and Children Hospital”, Sakakha, Al-Jouf Region. Kingdom of Saudi Arabia...

Apoptosis and its associated regulatory mechanisms are physiological events crucial to the maintenance of placental homeostasis; imbalance of these processes, however, such as occurs under various pathological conditions, may compromise placenta function and, consequently, pregnancy success. Increased apoptosis occurs in the placentas of pregnant women with several developmental disabilities, w...

Mitochondria are cellular organelles that have been reported to be altered in diabetes, being closely related to its associated complications. Moreover, mitochondrial biogenesis and function are essential for proper embryo development throughout the placentation period, occurring during organogenesis, when a great rate of congenital malformations have been associated with diabetic pregnancy. Th...