The dissociation of diacetyl dilute in krypton has been studied in a shock tube using laser schlieren densitometry at 1200-1800 K and reaction pressures of 55 +/- 2, 120 +/- 3, and 225 +/- 5 Torr. The experimentally determined rate coefficients show falloff and an ab initio/Master Equation/VRC-TST analysis was used to determine pressure-dependent rate coefficient expressions that are in good ag...

LY191145 is an N-alkylated glycopeptide antibiotic (the p-chlorobenzyl derivative of LY264826) with activity against vancomycin-susceptible and -resistant bacteria. Similar to vancomycin, LY191145 inhibited polymerization of peptidoglycan when muramyl pentapeptide served as a substrate but not when muramyl tetrapeptide was used, signifying a substrate-dependent mechanism of inhibition. Examinat...

Urea in biological fluids has been determined by a variety of direct and indirect procedures. Some indirect methods depend on the hydrolysis of urea with the enzyme urease to form ammonia, with subsequent quantitation of the ammonia by nesslerization (1-4). Undesirable features of these indirect methods are the use of relatively unstable reagents and loss of ammonia during the procedure. Direct...