Diaphragmatic hernia, secondary to transhiatal esophagectomy, appears to be a relatively infrequent diagnosis. Patients may be asymptomatic or present with various symptoms. Diagnosis of this condition requires a high index of suspicion. The most common cause of diaphragmatic hernia is widened esophageal hiatus during surgery; therefore, narrowing the hiatus can prevent conduit herniation. Here...

INTRODUCTION Respiratory muscle weakness is common in sepsis patients. Proinflammatory mediators produced during sepsis have been implicated in diaphragmatic contractile dysfunction, but the role of chemokines has not been explored. This study addressed the role of monocyte chemoattractant protein-1 (MCP-1, also known as CCL2), in the pathogenesis of diaphragmatic inflammation and weakness duri...

PURPOSE Characterization of the structural changes occurring in the pulmonary arteries resulting from surgically produced congenital diaphragmatic hernia in rabbits, with particular emphasis on the preventive effects of prenatal tracheal ligation or administration of intra-amniotic dexamethasone or surfactant. METHODS Twenty rabbit fetuses underwent surgical creation of a left-sided congenita...

RATIONALE Diaphragmatic Hernia is rare as complication of Colonoscopy. Diaphragmatic hernia as a complication of colonoscopy has been reported only few cases. Additionally, it is often misdiagnosed as other disease by clinicians due to their lack of related knowledge, which delays diagnosis of Diaphragmatic hernia and thus exacerbates the prognosis. PATIENT CONCERNS We report the case of a 66...

BACKGROUNDS/AIMS Postoperative diaphragmatic hernia, following liver resection, is a rare complication. METHODS Data of patients who underwent major hepatectomy for liver tumors, between 2011 and 2015 were retrospectively reviewed. The literature was searched for studies reporting the occurrence of diaphragmatic hernia following liver resection. RESULTS Diaphragmatic hernia developed in 2.3...

BACKGROUND Diaphragmatic dysfunction found in the patients with acute lung injury required prolonged mechanical ventilation. Mechanical ventilation can induce production of inflammatory cytokines and excess deposition of extracellular matrix proteins via up-regulation of transforming growth factor (TGF)-β1. Lumican is known to participate in TGF-β1 signaling during wound healing. The mechanisms...

INTRODUCTION Traumatic diaphragmatic hernias are an unusual presentation of trauma, and are observed in about 10% of diaphragmatic injuries. The diagnosis is often missed because of non-specific clinical signs, and the absence of additional intra-abdominal and thoracic injuries. CASE PRESENTATION We report a case of a 59-year-old Italian man hospitalized for abdominal pain and vomiting. His m...