نتایج جستجو برای: dichloroacetate
تعداد نتایج: 601 فیلتر نتایج به سال:
Journal:
:Archives of Disease in Childhood
1998
Journal:
:Acta Crystallographica Section E Structure Reports Online
2009
Journal:
:The FASEB Journal
2019
Journal:
:Journal of the American Society of Nephrology
2016
Journal:
:Nature
2014
Journal:
:Metabolites
2021
Journal:
:Biochimica et Biophysica Acta (BBA) - Bioenergetics
2016
Journal:
:Diabetologia
1980
Journal:
:The FASEB Journal
2014
2009
Y-L. Chung
H. Troy
I. R. Judson
J. R. Griffiths
M. O. Leach
T. R. Eykyn
INTRODUCTION: Dichloroacetate (DCA) is a pyruvate dehydrogenase kinase (PDK) inhibitor and is found to be an anti-cancer agent [1]. It causes the activation of pyruvate dehydrogenase (PDH) and increased glucose oxidation by promoting the influx of acetyl-CoA into the mitochondria and the Krebs cycle [1]. The hyperpolarised C experiment measures the conversion of labelled pyruvate to labelled la...
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